5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Product Name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- CAS No.
- 1060816-58-1
- Chemical Name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Synonyms
- 5-BroMo-2-chloro-7H-pyrro...;5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-2-chloro-;5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine ISO 9001：2015 REACH
- CBNumber
- CB02470148
- Molecular Formula
- C6H3BrClN3
- Formula Weight
- 232.47
- MOL File
- 1060816-58-1.mol
5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine Property
- Density
- 1.996±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 9.51±0.50(Predicted)
- Appearance
- Off-white to light brown Solid
- CAS DataBase Reference
- 1060816-58-1
Safety
- RIDADR
- UN2811
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B701063
- Product name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B701063
- Product name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- X8792
- Product name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 1g
- Price
- $136
- Updated
- 2021/12/16
- Product number
- 3H32-D-40
- Product name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 5G
- Price
- $250
- Updated
- 2021/12/16
- Product number
- OR317030
- Product name
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 1g
- Price
- $489
- Updated
- 2021/12/16
5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production
Synthesis
335654-06-3
1060816-58-1
The general procedure for the synthesis of 5-bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidines from 2-chloro-7H-pyrrolo[2,3-d]pyrimidines is as follows: N-bromosuccinimide (11,374.5 g, 64.04 mol, 2.0 eq.) was added in batches to 2-chloro-7H-pyrrolo[2,3-d]pyrimidines (4907.0 g, 31.91 mol, 1.0 equiv) in acetonitrile solution. The reaction was carried out at room temperature (25 °C) for 17 h. The completion of the reaction was monitored by TLC. Upon completion of the reaction, the reaction solution was slowly poured into 100 L of ice water and a large amount of solid was precipitated. The solid was collected by filtration and the filter cake was washed three times with 50 L of water and dried to give 7117.2 g of white solid product in 95.82% yield. The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO-d6): δ 12.78 (brs, 1H), 8.85 (s, 1H), 7.89 (s, 1H).
References
[1] Patent: CN105949196, 2016, A. Location in patent: Paragraph 0048; 0069; 0088 - 0091
5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine Suppliers
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 16077
- Advantage
- 64
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
View Lastest Price from 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine manufacturers
- Product
- 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine 1060816-58-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-02