6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- Product Name
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- CAS No.
- 1208082-91-0
- Chemical Name
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- Synonyms
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 6,8-dibromo-2-methyl-
- CBNumber
- CB02470168
- Molecular Formula
- C7H5Br2N3
- Formula Weight
- 290.94
- MOL File
- 1208082-91-0.mol
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Property
- Density
- 2.19±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.66±0.30(Predicted)
- Appearance
- Brown to dark brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D425898
- Product name
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- X9443
- Product name
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- Packaging
- 5g
- Price
- $265
- Updated
- 2021/12/16
- Product number
- HCH0367626
- Product name
- 6,8-DIBROMO-2-METHYLIMIDAZO[1,2-A]PYRAZINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $135.45
- Updated
- 2021/12/16
- Product number
- A230520
- Product name
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- Purity
- 95%
- Packaging
- 5g
- Price
- $205
- Updated
- 2021/12/16
- Product number
- CM168727
- Product name
- 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $219
- Updated
- 2021/12/16
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Chemical Properties,Usage,Production
Synthesis
78-95-5
24241-18-7
1208082-91-0
The reaction was carried out with 3,5-dibromopyrazin-2-amine (5 g, 19.8 mmol) and 2-chloroacetone (18.3 g, 198 mmol) in dioxane (40 ml) at reflux temperature for 16 hours. After completion of the reaction, the mixture was concentrated under reduced pressure and the resulting residue was ground with diisopropyl ether (DIPE) to give intermediate 101 (3.6 g, 55% yield).
References
[1] Patent: WO2010/89292, 2010, A1. Location in patent: Page/Page column 93
[2] Patent: US2012/83492, 2012, A1. Location in patent: Page/Page column 92
[3] Patent: US9993554, 2018, B2. Location in patent: Page/Page column 243
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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