Methyl 3-iodopyrazine-2-carboxylate
- Product Name
- Methyl 3-iodopyrazine-2-carboxylate
- CAS No.
- 173290-17-0
- Chemical Name
- Methyl 3-iodopyrazine-2-carboxylate
- Synonyms
- Methyl 3-iodo-2-pyrazinecarboxylate;Methyl 3-iodopyrazine-2-carboxylate;3-Iodopyrazine-2-carboxylate Methyl ester;3-Iodo-pyrazine-2-carboxylic acid Methyl ester;2-Pyrazinecarboxylic acid, 3-iodo-, methyl ester
- CBNumber
- CB02471408
- Molecular Formula
- C6H5IN2O2
- Formula Weight
- 264.02
- MOL File
- 173290-17-0.mol
Methyl 3-iodopyrazine-2-carboxylate Property
- Boiling point:
- 292.6±35.0℃ (760 Torr)
- Density
- 1.943±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 130.8±25.9℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- W3780
- Product name
- Methyl3-iodopyrazine-2-carboxylate
- Packaging
- 250mg
- Price
- $143
- Updated
- 2021/12/16
- Product number
- HCH0369346
- Product name
- METHYL-3-IODOPYRAZINE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.81
- Updated
- 2021/12/16
- Product number
- 121192
- Product name
- Methyl3-iodopyrazine-2-carboxylate
- Purity
- 97%
- Packaging
- 5g
- Price
- $1200
- Updated
- 2021/12/16
- Product number
- A373721
- Product name
- Methyl3-iodopyrazine-2-carboxylate
- Purity
- 98%
- Packaging
- 100mg
- Price
- $12
- Updated
- 2021/12/16
- Product number
- A373721
- Product name
- Methyl3-iodopyrazine-2-carboxylate
- Purity
- 98%
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
Methyl 3-iodopyrazine-2-carboxylate Chemical Properties,Usage,Production
Synthesis
16298-03-6
173290-17-0
General procedure for the synthesis of pyrazine-2-iodo-3-carboxylic acid methyl ester from 3-aminopyrazine-2-carboxylic acid methyl ester: Referring to the method of Example 15, isopentyl nitrite (5.2 mL, 39 mmol) was slowly added to a suspension of 3-aminopyrazine-2-carboxylic acid methyl ester (1.9 g, 12 mmol) in diiodomethane (20 mL). Subsequently, the reaction mixture was heated to 85 °C and stirred continuously at 100 °C for 15 hours. After completion of the reaction, the mixture was cooled to room temperature and left to stand. The crude product was purified by silica gel column chromatography to afford 1.4 g of the target product 2-iodo-3-carboxylic acid methyl pyrazine as a light yellow solid in 44% yield. The product was characterized by 1H-NMR (500 MHz, CDCl3): δ 4.04 (s, 3H), 8.47 (d, J = 2.1 Hz, 1H), 8.56 (d, J = 2.1 Hz, 1H).
References
[1] Patent: EP1602647, 2005, A1. Location in patent: Page/Page column 58
[2] Patent: WO2018/118670, 2018, A1. Location in patent: Page/Page column 180; 181
Methyl 3-iodopyrazine-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 3-iodopyrazine-2-carboxylate manufacturers
- Product
- Methyl 3-iodopyrazine-2-carboxylate 173290-17-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08