ChemicalBook > CAS DataBase List > Dehydroepiandrosterone acetate

Dehydroepiandrosterone acetate

Product Name
Dehydroepiandrosterone acetate
CAS No.
853-23-6
Chemical Name
Dehydroepiandrosterone acetate
Synonyms
PRASTERONE ACETATE;3β-Acetoxyandrost-5-en-17-one;DEHYDROISOANDROSTERONE ACETATE;3-β-acetoxy-5-androsten-17-one;DEHYDROISOANDROSTERONE 3-ACETATE;DHEA Acetate (Prasterone acetate);DHA, (10,13-DIMETHYL-17-OXO-1,2,3,4,7,8,9,11,12,14,15,16-DODECAHYDROCYCLOPENTA[A]PHENANTHREN-3-YL) ACETATE;skf2847;androstenoloneacetate;Prasterone Acetate API
CBNumber
CB0247928
Molecular Formula
C21H30O3
Formula Weight
330.47
MOL File
853-23-6.mol
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Dehydroepiandrosterone acetate Property

Melting point:
168-170 °C(lit.)
Boiling point:
407.89°C (rough estimate)
Density 
1.0998 (rough estimate)
vapor pressure 
0Pa at 20℃
refractive index 
1.5192 (estimate)
storage temp. 
Refrigerator
solubility 
Chloroform, DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
optical activity
[α]20/D +2.4°, c = 2 in ethanol
Water Solubility 
11.5mg/L(temperature not stated)
InChI
InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
InChIKey
NCMZQTLCXHGLOK-KJBVPOJVSA-N
SMILES
C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|
LogP
5.1 at 20℃
CAS DataBase Reference
853-23-6
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
BV8396810
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S960799
Product name
TRANS-DEHYDRO-ANDROSTERONE ACETATE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
S263141
Product name
ACETIC ACID DIMETHYL-OXO-TETRADECAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-YL ESTER
Purity
AldrichCPR
Packaging
10MG
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
390089
Product name
Dehydroisoandrosterone 3-acetate
Purity
97%
Packaging
5g
Price
$83.69
Updated
2025/07/31
Sigma-Aldrich
Product number
390089
Product name
Dehydroisoandrosterone 3-acetate
Purity
97%
Packaging
25g
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
S960799
Product name
TRANS-DEHYDRO-ANDROSTERONE ACETATE
Purity
AldrichCPR
Packaging
250mg
Price
$179
Updated
2024/03/01
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Dehydroepiandrosterone acetate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Menopausal syndrome

Uses

A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function

Definition

ChEBI: Prasterone acetate is a steroid ester.

Application

Dehydroepiandrosterone acetate (CAS No: 853-23-6, abbreviated as DHEA acetate) is an important pharmaceutical intermediate. It can be used as a raw material to produce testosterone, methyl testosterone, estradiol, and estriol. Recently, with the development of the pharmaceutical industry, more and more applications for DHEA acetate have been exploited[1].

Flammability and Explosibility

Not classified

Biological Activity

Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.

in vivo

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

References

[1] Chao Cheng. “Solubility determination and thermodynamic models for dehydroepiandrosterone acetate in mixed solvents of (ethyl acetate + methanol), (ethyl acetate + ethanol) and (ethyl acetate + isopropanol).” Journal of Chemical Thermodynamics 101 (2016): Pages 372-379.

Dehydroepiandrosterone acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dehydroepiandrosterone acetate manufacturers

Hainan Fubai Trading Co., LTD
Product
DHEA Acetate(Prasterone Acetate) 853-23-6
Price
US $600.00/kg
Min. Order
1kg
Purity
99
Supply Ability
999
Release date
2025-11-24
Ningbo Qingteng Plastic Cost.,Ltd.
Product
Superdrol Powder (methyl-drostanolone) 853-23-6
Price
US $10.00/box
Min. Order
1box
Purity
99
Supply Ability
in stock
Release date
2025-08-06
Ningbo Qingteng Plastic Cost.,Ltd.
Product
Dehydroisoandrosterone 3-acetate 853-23-6
Price
US $10.00/box
Min. Order
1box
Purity
99%
Supply Ability
1000Kilogram/Month
Release date
2025-07-24

853-23-6, Dehydroepiandrosterone acetateRelated Search:


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  • 5-ANDROSTEN-3-BETA-OL-17-ONE ACETATE
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  • Dehydroepiandrosterone acetate Prasterone acetate
  • ACETIC ACID DIMETHYL-OXO-TETRADECAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-YL ESTER
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  • DEHYDROEPIANDROSTERONE-3-ACETATE
  • DEHYDROISOANDROSTERONE 3-ACETATE
  • DEHYDROISOANDROSTERONE ACATATE
  • DEHYDROISOANDROSTERONE ACETATE
  • (3S,8R,9S,10R,13S)-10,13-dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate
  • ACETIC ACID (3S,8R,9S,10R,13S,14S)-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER
  • skf2847
  • acetic acid (10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl) ester
  • NCMZQTLCXHGLOK-ZKHIMWLXSA-N
  • DEHYDROISOANDROSTERONE 3-ACETATECRYSTALL INE
  • 3-β-acetoxy-5-androsten-17-one
  • 3b-Hydroxy-5-androstene-17-one acetate
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  • 3-β-Acetoxy-5-androsten-17-one, Prasterone acetate
  • 17-Oxoandrost-5-ene-3β-yl=acetate
  • 3β-Acetoxyandrost-5-en-17-one
  • 3β-Acetyloxyandrost-5-en-17-one
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  • [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate
  • [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] ethanoate
  • acetic acid [(3S,8R,9S,10R,13S,14S)-17-keto-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] ester
  • Dehydroisoandrosterone 3-acetate,3-β-Acetoxy-5-androsten-17-one, Prasterone acetate
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  • (3β)-3-(Acetyloxy)androst-5-en-17-one
  • 17-Oxoandrost-5-en-3β-yl Acetate
  • 3β-Acetoxy-5-androstene-17-one
  • 3β-Hydroxy-5-androstene-17-one Acetate
  • trans-Dehydroandrosterone Acetate Dehydroisoandrosterone Acetate
  • TRANS-DEHYDROANDROSTERONE ACETATE
  • 3-beta-acetoxydehydroepiandrosterone
  • 3-beta-hydroxy-andrest-5-en-17-onacetate
  • 3-beta-hydroxy-androst-5-en-17-onacetate
  • 3-beta-hydroxyandrost-5-en-17-oneacetate
  • androstenoloneacetate
  • Androst-5-en-17-one, 3-(acetyloxy)-, (3β)-
  • Abiraterone Impurity 68
  • DHEA ACETATE CAS:853-23-6
  • Abiraterone Impurity 40
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