(S)-N-Fmoc-2-(2'-propylenyl)alanine

Product Name: (S)-N-Fmoc-2-(2'-propylenyl)alanine
CAS No.: 288617-71-0
Chemical Name: (S)-N-Fmoc-2-(2'-propylenyl)alanine
Synonyms: FMoc-α-Me-Gly(Allyl)-OH;Fmoc-alpha-All-D-Ala-OH;Fmoc-α-Me-Gly(Allyl)-OH;(S)-N-FMOC-Α-ALLYLALANINE;(S)-N-Fmoc-A-Allylalanine;(S)-N-Fmoc-alpha-allylalanine;Fmoc-(S)-2-(2-propenyl)Ala-OH;Fmoc-(S)-2-(2-propenyl)alanine;(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-alpha-methyl-L-allylglycine
CBNumber: CB02485702
Molecular Formula: C21H21NO4
Formula Weight: 351.4
MOL File: 288617-71-0.mol

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(S)-N-Fmoc-2-(2'-propylenyl)alanine Property

Boiling point:: 564.3±45.0 °C(Predicted)
Density: 1.224
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: liquid
pka: 3.81±0.11(Predicted)
color: pale yellow
InChIKey: FNCSRFHDUZYOCR-NRFANRHFSA-N

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Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
TSCA: No

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

TRC

Product number: H950188
Product name: (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylpent-4-enoicacid
Packaging: 50mg
Price: $100
Updated: 2021/12/16

Usbiological

Product number: 278035
Product name: Fmoc-alpha-methyl-L-allylglycine
Packaging: 25mg
Price: $333
Updated: 2021/12/16

Activate Scientific

Product number: AS46299
Product name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpent-4-enoic acid
Purity: 97% ee
Packaging: 1g
Price: $383
Updated: 2021/12/16

Chem-Impex

Product number: 29359
Product name: Fmoc-α-methyl-L-allylglycine,≥99%(HPLC)
Purity: ≥99%(HPLC)
Packaging: 1G
Price: $483.39
Updated: 2021/12/16

ChemPep

Product number: 180765
Product name: Fmoc-α-Me-Gly(Allyl)-OH
Packaging: 1g
Price: $500
Updated: 2021/12/16

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(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemical Properties,Usage,Production

Uses

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

(S)-N-Fmoc-2-(2'-propylenyl)alanine Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-N-Fmoc-2-(2'-propylenyl)alanine Suppliers

China 55 India 1 United States 10 Global 66

Suzhou haiyu Biochem Industrial Co., LTD

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Advantage: 60

China DongFan Chemical Co.,LTD

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ChemPep, Inc.

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Sigma-Aldrich

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Shanghai Hisi bio-pharmaceutical Co. Ltd.

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Shanghai GL Peptide Ltd.

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Wuxi Asia Peptide Biotechnology Limited Company

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288617-71-0, (S)-N-Fmoc-2-(2'-propylenyl)alanineRelated Search:

α-Me-D-Gly(Pentenyl)-OtBu p-Nitrobenzoate Boc-α-Me-D-Gly(Allyl)-OEt (R)-alpha-Methylaspartic acid-4-tert-butyl ester, 98% ee, 98% FMoc-α-Me-D-Asp(OtBu)-OH (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-2-METHYL-HEPT-6-ENOIC ACID α-Me-Gly(Pentenyl)-OtBu p-Nitrobenzoate (S)-alpha-Methylaspartic acid-4-tert-butyl ester, 98% ee (R)-N-Fmoc-2-(2'-propylenyl)alanine (S)-2-METHYLCYSTEINE HYDROCHLORIDE FMoc-α-Me-D-Asn-OH FMoc-α-Me-D-Pro-OH Fmoc-alpha-methyl-D-leucine (S)-N-FMoc-2-(5'-pentenyl)alanine (S)-N-FMoc-2-(6'-heptenyl)alanine (S)-(+)-2-AMINO-2-METHYLBUTANEDIOIC ACID FMoc-α-Me-Asn-OH (R)-2-METHYLCYSTEINE HYDROCHLORIDE (S)-2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-2-METHYLHEPT-6-ENOIC ACID

(S)-N-Fmoc-2-(2'-propylenyl)alanine

(2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid

(S)-N-Fmoc-alpha-allylalanine

(S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine

Fmoc-alpha-methyl-L-allylglycine

(S)-N-FMOC-Α-ALLYLALANINE

FMoc-α-Me-Gly(Allyl)-OH

(S)-N-Fmoc-α-2-n-propenylalanine

Fmoc-(S)-2-(2-propenyl)alanine

Fmoc-(S)-2-(2-propenyl)Ala-OH

(9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH

Fmoc-alpha-All-D-Ala-OH

(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid

(S)-N-Fmoc-2-(2'-propenyl)alanine

(2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid

(S)-N-Fmoc-A-Allylalanine

4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)-

N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine

Fmoc-α-Me-Gly(Allyl)-OH

(S)-N-Fmoc-2-(2'-propylenyl)alanine

288617-71-0

α-Methyl Amino Acids