Methyl 2-(Boc-amino)isonicotinate
- Product Name
- Methyl 2-(Boc-amino)isonicotinate
- CAS No.
- 639091-75-1
- Chemical Name
- Methyl 2-(Boc-amino)isonicotinate
- Synonyms
- Methyl 2-(Boc-amino)isonicotinate;2-Boc-amino-isonicotinic acid methyl ester;Methyl 2-((tert-butoxycarbonyl)aMino)isonicotinate;2-tert-Butoxycarbonylamino-isonicotinic acid methyl ester;methyl 2-(tert-butoxycarbonylamino)pyridine-4-carboxylate;Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylate;2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pyridinecarboxylic acidmethylester;4-Pyridinecarboxylic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester
- CBNumber
- CB02499400
- Molecular Formula
- C12H16N2O4
- Formula Weight
- 252.27
- MOL File
- 639091-75-1.mol
Methyl 2-(Boc-amino)isonicotinate Property
- Melting point:
- 75.1～75.2℃
- Boiling point:
- 325.5±27.0 °C(Predicted)
- Density
- 1.203±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 12.12±0.70(Predicted)
Safety
- HS Code
- 2922390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
N-Bromosuccinimide Price
- Product number
- M295635
- Product name
- Methyl2-(Boc-amino)isonicotinate
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 018214
- Product name
- 2-(2,2-Dimethyl-propionylamino)-isonicotinic acidmethyl ester
- Packaging
- 500mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- 118101
- Product name
- Methyl 2-((tert-butoxycarbonyl)amino)isonicotinate
- Packaging
- 5g
- Price
- $301
- Updated
- 2021/12/16
- Product number
- 4H58-1-8C
- Product name
- Methyl 2-((tert-butoxycarbonyl)amino)isonicotinate
- Packaging
- 5G
- Price
- $356
- Updated
- 2021/12/16
- Product number
- Y6341
- Product name
- Methyl2-(tert-butoxycarbonylamino)isonicotinate
- Packaging
- 10g
- Price
- $370
- Updated
- 2021/12/16
Methyl 2-(Boc-amino)isonicotinate Chemical Properties,Usage,Production
Synthesis
A 500 mL round bottomed flask was charged with methyl 2-aminoisonicotinate (5.0 g, 32.9 mmol) and suspended in t-BuOH (200 mL). To this stirring solution was added di-tert-butyl dicarbonate (7.53 g, 34.5 mmol). The flask was vented and placed in an oil bath preheated to 50°C. The reaction mixture was let stir overnight. After 22 hours LCMS showed near complete conversion of starting material. The mixture was cooled to room temperature and filtered. The material was taken on without any further purification. Yield 5.93 g of white solid, Methyl 2-(Boc-amino)isonicotinate. 1H NMR (400 MHz, DMSO-d6) δ ppm 10.14 (1H, s), 8.43 (1H, dd, J=5.02, 0.75 Hz), 8.33 (1H, s), 7.45 (1H, dd, J=5.02, 1.51 Hz), 3.89 (3H, s), 1.48 (9H, s).
Methyl 2-(Boc-amino)isonicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
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