ChemicalBook > CAS DataBase List > 4-AMino-5-Methylpyridin-2-ol

4-AMino-5-Methylpyridin-2-ol

Product Name
4-AMino-5-Methylpyridin-2-ol
CAS No.
95306-64-2
Chemical Name
4-AMino-5-Methylpyridin-2-ol
Synonyms
4-AMino-5-Methylpyridin-2(1H)-one;4-amino-5-methyl-1H-pyridin-2-one;4-Amino-2-hydroxy-5-methylpyridine;Degarelix Impurity 4;Finerenone Impurity A;Finerenone Impurity 28;Felodipine Impurity 14;Finerenone intermediate;4-amino-5-methylpyridone;4-AMino-5-Methylpyridin-2-ol
CBNumber
CB02507291
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
95306-64-2.mol
More
Less

4-AMino-5-Methylpyridin-2-ol Property

Boiling point:
291.0±33.0℃ (760 Torr)
Density 
1.137±0.06 g/cm3 (20 ºC 760 Torr)
vapor pressure 
0-0Pa at 20-50℃
Flash point:
129.8±25.4℃
storage temp. 
2-8°C(protect from light)
pka
11.90±0.10(Predicted)
LogP
-0.51 at 20℃ and pH6.3
CAS DataBase Reference
95306-64-2
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
A617510
Product name
4-Amino-5-methylpyridin-2(1H)-one
Packaging
1g
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA16237
Product name
4-Amino-5-methyl-2(1H)-pyridinone
Packaging
2g
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-W022074
Product name
4-Amino-5-methylpyridin-2-ol
Purity
≥98.0%
Packaging
5g
Price
$260
Updated
2021/12/16
ChemScene
Product number
CS-W022074
Product name
4-Amino-5-methylpyridin-2-ol
Purity
≥98.0%
Packaging
1g
Price
$63
Updated
2021/12/16
AK Scientific
Product number
CS-W022074
Product name
4-Amino-5-methylpyridin-2-ol
Packaging
1g
Price
$80
Updated
2021/12/16
More
Less

4-AMino-5-Methylpyridin-2-ol Chemical Properties,Usage,Production

Description

4-AMino-5-Methylpyridin-2-ol belongs to the pyridine derivatives and is significantly alkaline. Its alcoholic hydroxyl group can undergo corresponding nucleophilic substitution reactions under alkaline conditions. It can be used as a material in organic synthesis and medicinal chemistry. The intermediate is used for the modification and production of drug molecules. For example, the compound can prepare selective mineralocorticoid receptor (MR) antagonist finerenone, which is used to lower the risk of severe kidney and heart problems.

Uses

4-Amino-5-methylpyridin-2(1H)-one has been used as a reactant for the synthesis of BAY 94-8862, a nonsteroidal antagonist of the mineralocorticoid receptor to be used for the treatment of cardiorenal diseases.

Synthesis

2-Chloro-4-amino-5-methylpyridine, dissolved in ethylene glycol, could be a starting material to synthesize 4-AMino-5-Methylpyridin-2-ol. The crude product could be precipitated by adding hydrochloric acid/methanol solution.

4-AMino-5-Methylpyridin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-AMino-5-Methylpyridin-2-ol Suppliers

China 234 Germany 1 India 11 United Kingdom 1 United States 7 Global 254
Jinan Guoding Pharmaceutical Technology Co., Ltd.
Tel
15665775653
Fax
053167801621
Email
sales@guodingpharma.com
Country
China
ProdList
480
Advantage
58
Hangzhou Chemtrue Bio-Tech Co.,Ltd.
Tel
0571-86828652 18857119830
Fax
0571-83522824
Email
sales@chemtrue-bio.com
Country
China
ProdList
314
Advantage
58
Nanjing Vcare PharmaTech Co., Ltd
Tel
025-58741518 17366379912
Email
sales@vcarepharmatech.com
Country
China
ProdList
462
Advantage
58
Jinan XinKe Pharmaceutical Technology Co., Ltd.
Tel
0531-88259693 17854196142
Fax
0531-88259693
Email
2820602043@qq.com
Country
China
ProdList
73
Advantage
58
Hangzhou Cheminspire Technology Co., Ltd.
Tel
0571-89081561; 10006559855
Fax
0571 89081561
Email
info@cheminspire.com
Country
China
ProdList
412
Advantage
58
Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958; 18866891188
Fax
0531-82777287
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
267
Advantage
58
Shandong Sihuan Pharmaceutical Co., Ltd.
Tel
0531-88993893 13335127975
Fax
QQ:787658403
Email
fairouz@sdsihuanpharm.com
Country
China
ProdList
91
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Changzhou Huanling Chemical Co., Ltd.
Tel
0519-89803565 13776850645
Fax
0519-89803575
Email
info4@huanlingchem.com
Country
China
ProdList
639
Advantage
68
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Jinan Chenghui Shuangda biological Co., LTD
Tel
0531-58897003 15550412551
Fax
0531-58897003
Email
market@jnchsd.com
Country
China
ProdList
217
Advantage
62
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098 13817598959
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
158
Advantage
55
Suzhou Chukai PharmaTech
Tel
0512-88812066
Fax
86-512-63926099
Email
wenlongfcb@qq.com
Country
China
ProdList
111
Advantage
62
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9452
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
Shenzhen HwaGen Pharmaceutical Co.,Ltd
Tel
0752-5538396 18927339850
Fax
0752-5319394
Email
sales1@rafflespt.com
Country
China
ProdList
216
Advantage
58
Shanghai Famo Bio-chemical Technology Company Ltd.
Tel
+862136680027 15800370750
Email
sales@famobiotech.com
Country
China
ProdList
509
Advantage
56
Ascepion Pharmaceuticals, Inc.
Tel
+86-512-86881668
Fax
+86-512-62956001
Country
China
ProdList
100
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
15026594951
Fax
0556-5030632
Email
rs@raise-chem.com
Country
China
ProdList
3204
Advantage
55
Valiant Co., Ltd.
Tel
0535-6101880
Fax
0535-6386989
Email
liutao@valiant-cn.com
Country
China
ProdList
234
Advantage
60
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1303
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3422
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shandong Zhongke Taidou Chemical Co., Ltd.
Tel
0531-88682302 18615650139
Fax
0531-62325738
Email
3303447386@qq.com
Country
China
ProdList
112
Advantage
62
Jiaxing Novartis Chemical Co., Ltd.
Tel
18957373295
Fax
-
Country
China
ProdList
1580
Advantage
58
Shanghai SE Pharm Co., Ltd
Tel
18112588827
Email
sales4@sepharm.com.cn
Country
China
ProdList
307
Advantage
60
Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd.
Tel
15981924004; 19943855286
Fax
0371-53392065
Email
Trizpharm@aliyun.com
Country
China
ProdList
1875
Advantage
56
Chengdu Laurelsci Tech Co., Ltd.
Tel
028-87983001
Fax
+86-28-86102331
Email
sales@laurelsci.com
Country
China
ProdList
50
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9798
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
BEIJING EAGLE SKY PHARMATECH CO., LTD
Tel
010-88755821 13911359480
Email
sophia_818@126.com
Country
China
ProdList
276
Advantage
55
Anqing CHICO Pharmaceutical Co., Ltd.
Tel
13585175604 13585175604
Fax
+86-25-52261140
Email
sales@chicopharm.com
Country
China
ProdList
498
Advantage
65
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6508
Advantage
58
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3319
Advantage
55
shandong XuanHong Pharmaceutical Technology Co.,Ltd
Tel
0531-88801869 15562622698
Fax
0531-88801867
Email
sciencechem@163.com
Country
China
ProdList
274
Advantage
55
ATK CHEMICAL COMPANY LIMITED
Tel
3429815786 13301662590
Fax
+86-21-51619052
Email
sales@atkchemical.com
Country
China
ProdList
10006
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Cangzhou Enke Pharma-tech Co., Ltd.
Tel
0317-5296180 15533709196
Fax
0317-5106596
Email
sale@enkepharma.com
Country
China
ProdList
1647
Advantage
55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
5463
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
9038
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Nanjing FuRuisi Medical Technology Co., Ltd.
Tel
025-83221260
Fax
02583221260
Email
renqing401@163.com
Country
China
ProdList
227
Advantage
55
Henan Anky Chemical Technology Co., Ltd.
Tel
17836913271
Fax
0374-8348899
Email
3224305243@qq.com
Country
China
ProdList
2718
Advantage
58
Nanijing m&m biotechnology Co. ,Ltd.
Tel
025-87782433 18021532344
Fax
025-87782433
Email
sales@marymebiotech.com
Country
China
ProdList
3928
Advantage
58
LinkChem Co.,Ltd.
Tel
021-021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
3000
Advantage
58
CHENGHUI PHARMACEUTICAL GROUP LTD
Tel
0531-58897070 15254140813
Fax
0531-58897046
Email
market@jnchsd.com
Country
China
ProdList
216
Advantage
58
More
Less

View Lastest Price from 4-AMino-5-Methylpyridin-2-ol manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD
Product
4-Amino-5-methyl-2(1H)-pyridinone 95306-64-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500kg
Release date
2023-03-16
Nanjing Fred Technology Co., Ltd
Product
4-Amino-2-hydroxy-5-methylpyridine 95306-64-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-04
Henan Fengda Chemical Co., Ltd
Product
4-AMino-5-Methylpyridin-2(1H)-one 95306-64-2
Price
US $10.00-3.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-29

95306-64-2, 4-AMino-5-Methylpyridin-2-olRelated Search:

4-AMino-5-benzyl-pyriMidine-2-thiol

  • 4-amino-5-methylpyridine-2(1H)-one
  • 4-Amino-2-hydroxy-5-methylpyridine
  • 4-AMino-5-Methyl-2-(1H)-pyridinone
  • 4-AMino-5-Methylpyridin-2(1H)-one
  • 4-AMino-5-Methylpyridin-2-ol
  • 2(1H)-Pyridinone, 4-amino-5-methyl-
  • 4-amino-5-methyl-1H-pyridin-2-one
  • 4-amino-5-methylpyridone
  • 4-amino-5-methyl-1,2-dihydropyridin-2-one
  • Finerenone Impurity 28
  • 4-Amino-5-methyl-2-hydroxypyridine
  • 4-amino-5-methylpyridine-2(1H)-on
  • Degarelix Impurity 4
  • Finerenone Impurity A
  • 4-Amino-5-methyl-2(1H)-pyridinone (4-Amino-5-methyl-2-pyridinol)
  • 4-Amino-5-methylpyridine-2-ol
  • Finerenone intermediate
  • 4-AMino-5-Methylpyridin-2Chemicalbook(1H)-one
  • Felodipine Impurity 14
  • 95306-64-2
  • Intermediate
  • 95306-64-2