1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
Uses- Product Name
- 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- CAS No.
- 649736-31-2
- Chemical Name
- 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- Synonyms
- CEDI-005;FMX15115-A4;1-(2-Fluoro-3-hydroxy-6-nitrophenyl);2-Fluoro-3-hydroxy-6-nitrophenylacetone;1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one;2-Propanone, 1-(2-fluoro-3-hydroxy-6-nitrophenyl)-
- CBNumber
- CB02514086
- Molecular Formula
- C9H8FNO4
- Formula Weight
- 213.16
- MOL File
- 649736-31-2.mol
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one Property
- Boiling point:
- 353.0±42.0 °C(Predicted)
- Density
- 1.417±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 5.58±0.24(Predicted)
- form
- Solid
- InChI
- InChI=1S/C9H8FNO4/c1-5(12)4-6-7(11(14)15)2-3-8(13)9(6)10/h2-3,13H,4H2,1H3
- InChIKey
- IPRZVDNMKMONNN-UHFFFAOYSA-N
- SMILES
- C(C1=C([N+]([O-])=O)C=CC(O)=C1F)C(=O)C
- CAS DataBase Reference
- 649736-31-2
Safety
- HS Code
- 2914790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F600868
- Product name
- 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- HCH0037302
- Product name
- 1-(2-FLUORO-3-HYDROXY-6-NITROPHENYL)PROPAN-2-ONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1033.73
- Updated
- 2021/12/16
- Product number
- 143736
- Product name
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- Purity
- 95%
- Packaging
- 1g
- Price
- $1458
- Updated
- 2021/12/16
- Product number
- 143736
- Product name
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- Purity
- 95%
- Packaging
- 5g
- Price
- $2916
- Updated
- 2021/12/16
- Product number
- CM254328
- Product name
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- Purity
- 95+%
- Packaging
- 5g
- Price
- $648
- Updated
- 2021/12/16
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one Chemical Properties,Usage,Production
Uses
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one (cas# 649736-31-2) is a useful research chemical.
Synthesis
121247-16-3
649736-31-2
Step 3b: A mixture of 1-(2,3-difluoro-6-nitrophenyl)propan-2-one (Compound 302, 4.30 g, 0.02 mol), sodium acetate (AcONa, 1.72 g, 0.021 mol) and N,N-dimethylformamide (DMF, 40 mL) was stirred and reacted for 12 hours at 100 °C. After completion of the reaction, the mixture was filtered and the solvent was removed by distillation under reduced pressure. The residue was extracted with ethyl acetate (100 mL) and the organic layer was washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate (MgSO?) and concentrated. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether = 1/1) to afford 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one (Compound 303, 2.3 g, 54%) as a light yellow solid.LCMS: 214 [M + 1]? ; 1H NMR (DMSO-d6): δ 2.30 (s, 3H), 4.26 (s, 2H), 7.67 (m, 1H), 8.05 (m, 1H).
References
[1] Patent: US2009/76044, 2009, A1. Location in patent: Page/Page column 27-28
[2] Organic Process Research and Development, 2014, vol. 18, # 1, p. 89 - 102
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one manufacturers
- Product
- 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one 649736-31-2
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-04-27
- Product
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one 649736-31-2
- Price
- US $0.00/KG
- Min. Order
- 1g
- Purity
- 99
- Supply Ability
- 100kg
- Release date
- 2020-08-10
- Product
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one 649736-31-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2019-12-30