N-Ethyl-p-menthane-3-carboxamide
- Product Name
- N-Ethyl-p-menthane-3-carboxamide
- CAS No.
- 39711-79-0
- Chemical Name
- N-Ethyl-p-menthane-3-carboxamide
- Synonyms
- WS-3;Menthol Carboxamide;ETHYL MENTHANE CARBOXAMIDE;Cooling Agent WS-3;N,2,3-trimethyl-2isopropl butanamide;FEMA 3455;Cooling taste agent ws-23;N-Ethyl-PARA-Menthan-3-Carboxamide;N-ETHYL-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE;N-Ethyl-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide
- CBNumber
- CB0252522
- Molecular Formula
- C13H25NO
- Formula Weight
- 211.34
- MOL File
- 39711-79-0.mol
N-Ethyl-p-menthane-3-carboxamide Property
- Melting point:
- 87-102 °C
- Boiling point:
- 351.04°C (rough estimate)
- alpha
- D -49 to -54°
- Density
- 0.9305 (rough estimate)
- vapor pressure
- 0.007Pa at 25℃
- refractive index
- 1.4410 (estimate)
- FEMA
- 3455 | N-ETHYL-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: ≥ 100 mg/mL (473.17 mM); Water: < 0.1 mg/mL (insoluble)
- pka
- 16.27±0.60(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- Odor
- at 25.00 % in dipropylene glycol. mild mentholic minty
- Odor Type
- minty
- Water Solubility
- insoluble
- JECFA Number
- 1601
- Merck
- 14,3825
- InChIKey
- VUNOFAIHSALQQH-UHFFFAOYSA-N
- LogP
- 2.902 at 25℃
- CAS DataBase Reference
- 39711-79-0(CAS DataBase Reference)
- EPA Substance Registry System
- Cyclohexanecarboxamide, N-ethyl-5-methyl-2-(1-methylethyl)- (39711-79-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- W345501
- Product name
- N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
- Purity
- 99%
- Packaging
- sample-k
- Price
- $54.6
- Updated
- 2024/03/01
- Product number
- W345501
- Product name
- N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
- Purity
- 99%, FG
- Packaging
- 100g
- Price
- $144
- Updated
- 2024/03/01
- Product number
- W345501
- Product name
- N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
- Purity
- 99%, FG
- Packaging
- 1kg
- Price
- $690
- Updated
- 2024/03/01
- Product number
- W345501
- Product name
- N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
- Purity
- 99%, FG
- Packaging
- 5kg
- Price
- $1460
- Updated
- 2024/03/01
- Product number
- E0796
- Product name
- N-Ethyl-p-menthane-3-carboxamide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $19
- Updated
- 2024/03/01
N-Ethyl-p-menthane-3-carboxamide Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Chemical Properties
N-ethyl-p-menthane-3-carboxamide is an odorless white, crystalline solid. The compound has a strong and clear physiological cooling effect and is used mainly in oral care products.
Chemical Properties
Slight menthol-like cooling effect aroma
Uses
WS 3 is a selective transient receptor potential melastatin-8 ligand.
Uses
Physiological coolant in foods, beverages, toiletries, cosmetics and pharmaceuticals.
Definition
ChEBI: Ethyl menthane carboxamide is a p-menthane monoterpenoid.
Aroma threshold values
Aroma characteristics at 1.0%. Virtually odorless
Taste threshold values
Taste characteristics at 10 to 100 ppm. Intense lingering cooling. The cooling sensation builds slow but steadily and grows to a lingering cooling mouthfeel with a slightly camphoraceous and minty character.
Flammability and Explosibility
Not classified
Trade name
Winsense WS-3 (Renessenz)
Biological Activity
Cooling agent that is an agonist at TRPM8 receptors (EC 50 = 3.7 μ M).
Synthesis
0.89
g (0.0091 mol) of polyphosphoric acid (85%) and 0.42 g (0.0091 mol) of
ethanol were weighed. 0.54 g (0.0046 mol) of diethylcarbonate was added
dropwise slowly while cooling in an ice bath, wherein the temperature
increases slightly. After about 5 minutes, 0.5 g (0.0030 mol) of
p-menthane-3-carbonitrile was added. The reaction solution was heated
and stirred for 102 hours at 150??C. At the end of the reaction by GC,
about 70% of desired N-Ethyl-p-menthane-3-carboxamide was formed.
N-Ethyl-p-menthane-3-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
N-Ethyl-p-menthane-3-carboxamide Suppliers
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- Country
- United Kingdom
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View Lastest Price from N-Ethyl-p-menthane-3-carboxamide manufacturers
- Product
- Cooling Agent Ws-3 39711-79-0
- Price
- US $180.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-30
- Product
- N-Ethyl-p-menthane-3-carboxamide 39711-79-0
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-19
- Product
- N-Ethyl-p-menthane-3-carboxamide 39711-79-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2023-12-23