Imidazo[1,2-b]pyridazine, 6-bromo-
Uses- Product Name
- Imidazo[1,2-b]pyridazine, 6-bromo-
- CAS No.
- 1159977-65-7
- Chemical Name
- Imidazo[1,2-b]pyridazine, 6-bromo-
- Synonyms
- 6-Bromoimidazo[1,2-b]pyri...;6-BroMoiMidazo[1,2-b]pyridazin;6-BroMoiMidazo[1,2-b]pyridazine;Imidazo[1,2-b]pyridazine, 6-bromo-
- CBNumber
- CB02525233
- Molecular Formula
- C6H4BrN3
- Formula Weight
- 198.02
- MOL File
- 1159977-65-7.mol
Imidazo[1,2-b]pyridazine, 6-bromo- Property
- Density
- 1.89±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.60±0.30(Predicted)
- Appearance
- Off-white to light brown Solid
- CAS DataBase Reference
- 1159977-65-7
N-Bromosuccinimide Price
- Product number
- B699743
- Product name
- 6-Bromoimidazo[1,2-b]pyridazine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3H32-9-9Z
- Product name
- 6-Bromoimidazo[1,2-b]pyridazine
- Purity
- 97.0%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 068793
- Product name
- 6-Bromoimidazo[1,2-b]pyridazine
- Purity
- >95%
- Packaging
- 250mg
- Price
- $378
- Updated
- 2021/12/16
- Product number
- HCH0367829
- Product name
- 6-BROMOIMIDAZO[1,2-B]PYRIDAZINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.17
- Updated
- 2021/12/16
- Product number
- 068793
- Product name
- 6-Bromoimidazo[1,2-b]pyridazine
- Purity
- >95%
- Packaging
- 500mg
- Price
- $607
- Updated
- 2021/12/16
Imidazo[1,2-b]pyridazine, 6-bromo- Chemical Properties,Usage,Production
Uses
Imidazo[1,2-b]pyridazine, 6-bromo- is a heterocyclic derivative that can be used as a pharmaceutical intermediate.
Synthesis
88497-27-2
2032-35-1
1159977-65-7
GENERAL STEPS: To a solution of 6-bromopyridazin-3-amine (3.48 g, 20 mmol) in ethanol/water (5:1, 180 mL) was added 2-bromo-1,1-diethoxyethane (11.8 g, 60 mmol) followed by p-toluenesulfonic acid (20.6 mg, 0.12 mmol). The reaction mixture was stirred at 80 °C for 16 h. After completion of the reaction, the solvent was concentrated in vacuum by rotary evaporator. The resulting solid was washed with distilled water (4 mL), collected by filtration through a Büchner funnel and dried overnight in a vacuum oven at 40 °C to afford 6-bromoimidazo[1,2-b]pyridazine as a gray solid (3.9 g, 100% yield). Mass spectrum (ESI, positive ion mode) m/z: 198.1 [M + H]+; 1H NMR (400 MHz, CDCl3): δ 8.71 (d, J = 9.6 Hz, 1H), 8.44 (d, J = 1.6 Hz, 1H), 8.33 (d, J = 1.9 Hz, 1H), 7.97 (d, J = 9.6 Hz, 1H).
References
[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0288
Imidazo[1,2-b]pyridazine, 6-bromo- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Imidazo[1,2-b]pyridazine, 6-bromo- manufacturers
- Product
- 6-Bromoimidazo[1,2-b]pyridazine 1159977-65-7
- Price
- US $105.00-400.00/g
- Min. Order
- 5g
- Purity
- 0.97
- Supply Ability
- 25kg
- Release date
- 2023-12-07
- Product
- 6-BroMoiMidazo[1,2-b]pyridazine 1159977-65-7
- Price
- US $0.00-0.00/G
- Min. Order
- 1G
- Purity
- 98%min
- Supply Ability
- 50kgs/month
- Release date
- 2022-09-11