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ChemicalBook > CAS DataBase List > Imidazo[1,2-b]pyridazine, 6-bromo-

Imidazo[1,2-b]pyridazine, 6-bromo-

Uses
Product Name
Imidazo[1,2-b]pyridazine, 6-bromo-
CAS No.
1159977-65-7
Chemical Name
Imidazo[1,2-b]pyridazine, 6-bromo-
Synonyms
6-Bromoimidazo[1,2-b]pyri...;6-BroMoiMidazo[1,2-b]pyridazin;6-BroMoiMidazo[1,2-b]pyridazine;Imidazo[1,2-b]pyridazine, 6-bromo-
CBNumber
CB02525233
Molecular Formula
C6H4BrN3
Formula Weight
198.02
MOL File
1159977-65-7.mol
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Imidazo[1,2-b]pyridazine, 6-bromo- Property

Density 
1.89±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
3.60±0.30(Predicted)
Appearance
Off-white to light brown Solid
CAS DataBase Reference
1159977-65-7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B699743
Product name
6-Bromoimidazo[1,2-b]pyridazine
Packaging
10mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-9Z
Product name
6-Bromoimidazo[1,2-b]pyridazine
Purity
97.0%
Packaging
250mg
Price
$240
Updated
2021/12/16
Matrix Scientific
Product number
068793
Product name
6-Bromoimidazo[1,2-b]pyridazine
Purity
>95%
Packaging
250mg
Price
$378
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0367829
Product name
6-BROMOIMIDAZO[1,2-B]PYRIDAZINE
Purity
95.00%
Packaging
5MG
Price
$503.17
Updated
2021/12/16
Matrix Scientific
Product number
068793
Product name
6-Bromoimidazo[1,2-b]pyridazine
Purity
>95%
Packaging
500mg
Price
$607
Updated
2021/12/16
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Imidazo[1,2-b]pyridazine, 6-bromo- Chemical Properties,Usage,Production

Uses

Imidazo[1,2-b]pyridazine, 6-bromo- is a heterocyclic derivative that can be used as a pharmaceutical intermediate.

Synthesis

88497-27-2

2032-35-1

1159977-65-7

GENERAL STEPS: To a solution of 6-bromopyridazin-3-amine (3.48 g, 20 mmol) in ethanol/water (5:1, 180 mL) was added 2-bromo-1,1-diethoxyethane (11.8 g, 60 mmol) followed by p-toluenesulfonic acid (20.6 mg, 0.12 mmol). The reaction mixture was stirred at 80 °C for 16 h. After completion of the reaction, the solvent was concentrated in vacuum by rotary evaporator. The resulting solid was washed with distilled water (4 mL), collected by filtration through a Büchner funnel and dried overnight in a vacuum oven at 40 °C to afford 6-bromoimidazo[1,2-b]pyridazine as a gray solid (3.9 g, 100% yield). Mass spectrum (ESI, positive ion mode) m/z: 198.1 [M + H]+; 1H NMR (400 MHz, CDCl3): δ 8.71 (d, J = 9.6 Hz, 1H), 8.44 (d, J = 1.6 Hz, 1H), 8.33 (d, J = 1.9 Hz, 1H), 7.97 (d, J = 9.6 Hz, 1H).

References

[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0288

Imidazo[1,2-b]pyridazine, 6-bromo- Preparation Products And Raw materials

Raw materials

Preparation Products

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Imidazo[1,2-b]pyridazine, 6-bromo- Suppliers

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View Lastest Price from Imidazo[1,2-b]pyridazine, 6-bromo- manufacturers

Shanghai UCHEM Inc.
Product
6-Bromoimidazo[1,2-b]pyridazine 1159977-65-7
Price
US $105.00-400.00/g
Min. Order
5g
Purity
0.97
Supply Ability
25kg
Release date
2023-12-07
Shanghai Rlavie Technology Co ltd
Product
6-BroMoiMidazo[1,2-b]pyridazine 1159977-65-7
Price
US $0.00-0.00/G
Min. Order
1G
Purity
98%min
Supply Ability
50kgs/month
Release date
2022-09-11