6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE

Product Name: 6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE
CAS No.: 30384-96-4
Chemical Name: 6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE
Synonyms: 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde;6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE;IMidazo[1,2-a]pyridine-3-carboxaldehyde, 6-broMo-
CBNumber: CB82451918
Molecular Formula: C8H5BrN2O
Formula Weight: 225.04
MOL File: 30384-96-4.mol

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6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: Light yellow to yellow Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B694500
Product name: 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B694500
Product name: 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde
Packaging: 1g
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140465
Product name: 6-Bromoimidazo[1,2-a]pyridine-3-carboxaldehyde
Packaging: 1g
Price: $320
Updated: 2021/12/16

Apolloscientific

Product number: OR350033
Product name: 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde
Packaging: 1g
Price: $247
Updated: 2021/12/16

Matrix Scientific

Product number: 072455
Product name: 6-Bromoimidazo[1,2-a]pyridine-3-carboxaldehyde
Purity: 95+%
Packaging: 1g
Price: $250
Updated: 2021/12/16

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6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

1072-97-5

2065-75-0

30384-96-4

Step 1: 2-Bromomalonaldehyde (5230 mg, 34.68 mmol) was added to an acetonitrile solution of 2-amino-5-bromopyridine (5000 mg, 28.90 mmol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution and extracted with ethyl acetate (EtOAc). The organic layer was washed with brine and dried over anhydrous sodium sulfate. The organic layer was concentrated under reduced pressure, and the resulting crude product was purified by silica gel column chromatography using gradient elution with ethyl acetate-petroleum ether to afford 6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde. Yield: 53%; 1H NMR (DMSO-d6, 300 MHz): δ 9.94 (s, 1H), 9.50 (s, 1H), 8.54 (s, 1H), 7.86-7.85 (m, 2H); MS (m/z): 226 (M + 1)+.

References

[1] Patent: WO2011/55320, 2011, A1. Location in patent: Page/Page column 44
[2] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 17, p. 5837 - 5844
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 21, p. 8781 - 8800
[4] Chinese Chemical Letters, 2015, vol. 26, # 1, p. 118 - 120

6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE Suppliers

China 79 India 1 Japan 1 United Kingdom 2 United States 12 Global 95

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30384-96-4, 6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDERelated Search:

6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID 6-Bromoimidazo[1,2-a]pyrazine-3-carbaldehyde Imidazo[1,2-a]pyridine IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE 6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-(4-FLUORO-PHENYL)-IMIDAZO[1,2-A]-PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 6-Bromo-2-phenyl-imidazo[1,2-a]pyridine-3-carboxaldehyde 6-BROMO-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID 6-BROMO-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 6-BROMO-2-(3-METHOXY-PHENYL)-IMIDAZO[1,2-A]-PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-(4-NITRO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-(3-NITRO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 6-BROMO-2-(3,4-DIMETHOXY-PHENYL)-IMIDAZO[1,2-A]-PYRIDINE-3-CARBALDEHYDE 2-BIPHENYL-4-YL-6-BROMO-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE BUTTPARK 87\01-81

6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde

IMidazo[1,2-a]pyridine-3-carboxaldehyde, 6-broMo-

6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE

30384-96-4

PI3K inhibitors

Heterocycle-Pyridine series