ChemicalBook > CAS DataBase List > 2,3-Difluorophenylacetic acid

2,3-Difluorophenylacetic acid

Product Name
2,3-Difluorophenylacetic acid
CAS No.
145689-41-4
Chemical Name
2,3-Difluorophenylacetic acid
Synonyms
Acid 2,3-difluoro;RARECHEM AL BO 0630;2,3-Difluorophenylacetic acid;2,3-DIFLUOROBENZENEACETIC ACID;2,3-Difluorophenylaceticacid97%;2,3-DifluorophenylaceticAcid>Benzeneacetic acid, 2,3-difluoro-;2-(2,3-DIFLUOROPHENYL)ACETIC ACID;2 3-DIFLUOROPHENYLACETIC ACID 97%;2,3-Difluorophenylacetic acid ISO 9001：2015 REACH
CBNumber
CB0252890
Molecular Formula
C8H6F2O2
Formula Weight
172.13
MOL File
145689-41-4.mol
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2,3-Difluorophenylacetic acid Property

Melting point:
116-119 °C (lit.)
Boiling point:
258.1±25.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.81±0.10(Predicted)
form 
Crystalline Powder
color 
White to off-white
InChI
InChI=1S/C8H6F2O2/c9-6-3-1-2-5(8(6)10)4-7(11)12/h1-3H,4H2,(H,11,12)
InChIKey
UXSQXUSJGPVOKT-UHFFFAOYSA-N
SMILES
C1(CC(O)=O)=CC=CC(F)=C1F
CAS DataBase Reference
145689-41-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
290416
Product name
2,3-Difluorophenylacetic acid
Purity
97%
Packaging
1g
Price
$63.5
Updated
2023/01/07
TCI Chemical
Product number
D3889
Product name
2,3-Difluorophenylacetic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$125
Updated
2025/07/31
TCI Chemical
Product number
D3889
Product name
2,3-Difluorophenylacetic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$602
Updated
2022/04/27
TRC
Product number
D451193
Product name
2,3-Difluorophenylacetic Acid
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
D451193
Product name
2,3-Difluorophenylacetic Acid
Packaging
250mg
Price
$55
Updated
2021/12/16
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2,3-Difluorophenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

2,3-Difluorophenylacetic acid may be used in chemical synthesis.

Synthesis

1036273-31-0

145689-41-4

Example 19: Synthesis of 2-(2,3-difluorophenyl)acetic acid Using methyl 2,3-difluorophenylacetate (CAS: 1036273-31-0) as a raw material, the following was performed: 1. 10 mL of water and 0.8 mL of 30% sodium hydroxide solution were added to 0.3 g of methyl 2,3-difluorophenylacetate. 2. the reaction mixture was stirred at 60 °C for 1 h until the reaction was complete. 3. After completion of the reaction, the mixture was acidified to pH=1 with concentrated hydrochloric acid. 4. The product was separated by filtration to afford 2-(2,3-difluorophenyl)acetic acid as a white solid in a yield of 0.2 g (72% yield). Product Characterization: 1H-NMR (300 MHz, CDCl3): δ (ppm): 3.75 (s, 2H); 7.01-7.06 (m, 3H); 9.4 (bs, 1H).

References

[1] Patent: WO2008/78350, 2008, A2. Location in patent: Page/Page column 23

2,3-Difluorophenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3-Difluorophenylacetic acid manufacturers

Hebei Fengjia New Material Co., Ltd
Product
2,3-Difluorophenylacetic acid 145689-41-4
Price
US $3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000
Release date
2024-09-04
Hebei Chuanghai Biotechnology Co., Ltd
Product
2,3-Difluorophenylacetic acid 145689-41-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-10
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2,3-Difluorophenylacetic acid 145689-41-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-25

145689-41-4, 2,3-Difluorophenylacetic acidRelated Search:

alpha-Hydroxy-2,3-difluorophenylacetic acid,à-hydroxy-2,3-difluorophenylacetic acid 2-CHLORO-4,5-DIFLUOROPHENYLACETIC ACID 2,3,6-TRIFLUOROPHENYLACETIC ACID 2,3,4-TRIFLUOROPHENYLACETIC ACID 2,3,5-TRIFLUOROPHENYLACETIC ACID 1-(2-CHLORO-4-FLUOROPHENYL)CYCLOPENTANECARBOXYLIC ACID, 98 2,3,4,5,6-PENTAFLUOROPHENYLACETIC ACID 2,3-DIFLUORO-4-METHYLPHENYLACETIC ACID METHYL 2-CHLORO-4-FLUOROPHENYLACETATE 98 à-hydroxy-2,5-difluorophenylacetic acid α,α-Difluorophenylacetic acid 2,4-Difluorophenylacetic acid 97%,2,4-DIFLUOROPHENYLACETIC ACID 3,4-Difluorophenylacetic acid 98%,3,4-DIFLUOROPHENYLACETIC ACID 3,4-DIFLUOROPHENYLACETIC ACID METHYL ESTER 2,6-Difluorophenylacetic acid 97%,2,6-DIFLUOROPHENYLACETIC ACID à-hydroxy-2,4-difluorophenylacetic acid,alpha-Hydroxy-2,4-difluorophenylacetic acid alpha-Hydroxy-3,4-difluorophenylacetic acid,à-hydroxy-3,4-difluorophenylacetic acid 3,5-DIFLUOROPHENYLACETIC ACID,3,5-Difluorophenylacetic acid 99%

  • RARECHEM AL BO 0630
  • 2-(2,3-DIFLUOROPHENYL)ACETIC ACID
  • 2,3-DIFLUOROBENZENEACETIC ACID
  • 2 3-DIFLUOROPHENYLACETIC ACID 97%
  • 2,3-Difluorophenylaceticacid97%
  • 2,3-Difluorophenylacetic acid
  • Benzeneacetic acid, 2,3-difluoro-
  • Acid 2,3-difluoro
  • 2,3-DifluorophenylaceticAcid&gt
  • 2,3-Difluorophenylacetic acid ISO 9001：2015 REACH
  • 145689-41-4
  • F2C6H3CH2CO2H
  • Building Blocks
  • Carboxylic Acids
  • Carbonyl Compounds
  • C8
  • Organic Building Blocks
  • Aromatic Phenylacetic Acids and Derivatives
  • Phenylacetic acid
  • C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • Fluorobenzene Series
  • Phenylacetic acid series