ChemicalBook > CAS DataBase List > YIL 781

YIL 781

Product Name: YIL 781
CAS No.: 875258-85-8
Chemical Name: YIL 781
Synonyms: CS-765;YIL 781;YIL 781, >=98%;YIL781, CID 23631116;YIL-781 hydrochloride;YIL 781, 10 mM in DMSO;YIL781 hydrochloride, Ghrelin receptor antagonist;(S)-6-(4-Fluorophenoxy)-3-[(1-isopropylpiperidin-3-yl)methyl]-2-methylquinazolin-4(3H)-one;6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone;4(3H)-Quinazolinone, 6-(4-fluorophenoxy)-2-Methyl-3-[[(3S)-1-(1-Methylethyl)-3-piperidinyl]Methyl]-
CBNumber: CB02535706
Molecular Formula: C24H28FN3O2
Formula Weight: 409.5
MOL File: 875258-85-8.mol

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YIL 781 Property

Boiling point:: 532.3±58.0 °C(Predicted)
Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: H2O: soluble2mg/mL, clear (warmed)
form: powder
pka: 10.03±0.50(Predicted)
color: white to yellow to light brown
Water Solubility: H2O: 2mg/mL, clear (warmed)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1148
Product name: YIL-781 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $130
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1148
Product name: YIL-781 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $519
Updated: 2025/07/31

Tocris

Product number: 3959
Product name: YIL-781 hydrochloride
Purity: ≥98%(HPLC)
Packaging: 5
Price: $125
Updated: 2021/12/16

Tocris

Product number: 3959
Product name: YIL-781 hydrochloride
Purity: ≥98%(HPLC)
Packaging: 25
Price: $476
Updated: 2021/12/16

TRC

Product number: Y100650
Product name: YIL781
Packaging: 10mg
Price: $160
Updated: 2021/12/16

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YIL 781 Chemical Properties,Usage,Production

Uses

YIL 781 is a ghrelin receptor antagonist useful in the treatment of obesity and diabetes.

Biological Activity

YIL-781 is a potent antagonist (Ki = 17 nM) of the growth hormone secretagogue receptor (GHS-R1). YIL-781 blocks ghrelin-induced reduction of insulin secretion in r at islets. In vivo, the compound YIL-781 improves glucose tolerance and reduces weight gain.

YIL 781 Preparation Products And Raw materials

Raw materials

Preparation Products

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875258-85-8, YIL 781Related Search:

YIL 781

4(3H)-Quinazolinone, 6-(4-fluorophenoxy)-2-Methyl-3-[[(3S)-1-(1-Methylethyl)-3-piperidinyl]Methyl]-

6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone hydrochloride

YIL-781 hydrochloride

YIL 781, >=98%

(S)-6-(4-Fluorophenoxy)-3-[(1-isopropylpiperidin-3-yl)methyl]-2-methylquinazolin-4(3H)-one

YIL781, CID 23631116

CS-765

6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone

YIL781 hydrochloride, Ghrelin receptor antagonist

YIL 781, 10 mM in DMSO

875258-85-8