ChemicalBook > CAS DataBase List > YIL 781
YIL 781
- Product Name
- YIL 781
- CAS No.
- 875258-85-8
- Chemical Name
- YIL 781
- Synonyms
- CS-765;YIL 781;YIL 781, >=98%;YIL781, CID 23631116;YIL-781 hydrochloride;YIL 781, 10 mM in DMSO;YIL781 hydrochloride, Ghrelin receptor antagonist;(S)-6-(4-Fluorophenoxy)-3-[(1-isopropylpiperidin-3-yl)methyl]-2-methylquinazolin-4(3H)-one;6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone;4(3H)-Quinazolinone, 6-(4-fluorophenoxy)-2-Methyl-3-[[(3S)-1-(1-Methylethyl)-3-piperidinyl]Methyl]-
- CBNumber
- CB02535706
- Molecular Formula
- C24H28FN3O2
- Formula Weight
- 409.5
- MOL File
- 875258-85-8.mol
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YIL 781 Property
- Boiling point:
- 532.3±58.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- H2O: soluble2mg/mL, clear (warmed)
- form
- powder
- pka
- 10.03±0.50(Predicted)
- color
- white to yellow to light brown
- Water Solubility
- H2O: 2mg/mL, clear (warmed)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1148
- Product name
- YIL-781 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $89.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML1148
- Product name
- YIL-781 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $594
- Updated
- 2024/03/01
Tocris
- Product number
- 3959
- Product name
- YIL-781 hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 25
- Price
- $476
- Updated
- 2021/12/16
Tocris
- Product number
- 3959
- Product name
- YIL-781 hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $125
- Updated
- 2021/12/16
TRC
- Product number
- Y100650
- Product name
- YIL781
- Packaging
- 10mg
- Price
- $160
- Updated
- 2021/12/16
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YIL 781 Chemical Properties,Usage,Production
Uses
YIL 781 is a ghrelin receptor antagonist useful in the treatment of obesity and diabetes.
Biological Activity
YIL-781 is a potent antagonist (Ki = 17 nM) of the growth hormone secretagogue receptor (GHS-R1). YIL-781 blocks ghrelin-induced reduction of insulin secretion in r at islets. In vivo, the compound YIL-781 improves glucose tolerance and reduces weight gain.
YIL 781 Preparation Products And Raw materials
Raw materials
Preparation Products
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