Notoginsenoside Ft1

ChemicalBook > CAS DataBase List > Notoginsenoside Ft1

Product Name: Notoginsenoside Ft1
CAS No.: 155683-00-4
Chemical Name: Notoginsenoside Ft1
Synonyms: product/153944;Notoginsenoside Ft1;β-D-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-;(3beta,12beta,20R)-12,20-Dihydroxydammar-24-en-3-yl O-beta-D-xylopyranosyl-(1- 2)-O-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranoside;(2S,3R,4S,5R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
CBNumber: CB02535807
Molecular Formula: C47H80O17
Formula Weight: 917.13
MOL File: 155683-00-4.mol

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Notoginsenoside Ft1 Property

Boiling point:: 997.8±65.0 °C(Predicted)
Density: 1.36±0.1 g/cm3(Predicted)
solubility: DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 5 mg/ml
form: A crystalline solid
pka: 12.84±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24976
Product name: Notoginsenoside Ft1
Purity: ≥95%
Packaging: 1mg
Price: $26
Updated: 2024/03/01

Cayman Chemical

Product number: 24976
Product name: Notoginsenoside Ft1
Purity: ≥95%
Packaging: 500μg
Price: $32
Updated: 2023/01/06

Cayman Chemical

Product number: 24976
Product name: Notoginsenoside Ft1
Purity: ≥95%
Packaging: 5mg
Price: $83
Updated: 2024/03/01

Cayman Chemical

Product number: 24976
Product name: Notoginsenoside Ft1
Purity: ≥95%
Packaging: 10mg
Price: $102
Updated: 2024/03/01

ApexBio Technology

Product number: N2245
Product name: NotoginsenosideFt1
Packaging: 20mg
Price: $400
Updated: 2021/12/16

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Notoginsenoside Ft1 Chemical Properties,Usage,Production

Description

Notoginsenoside Ft₁ is a saponin originally isolated from P. notoginseng with diverse biological activities. It induces proliferation, migration, and tube formation of human umbilical vein endothelial cells (HUVECs) via nuclear translocation of hypoxia-inducible factor-1α (HIF-1α) and activation of the PI3K/AKT and Raf/MEK/ERK signaling pathways in a manner dependent on mammalian target of rapamycin (mTOR). Notoginsenoside Ft₁ (45 μM) induces cell cycle arrest at the S and G₂/M phases and promotes apoptosis of SH-SY5Y cells. It increases cGMP levels and induces relaxation of isolated precontracted rat mesenteric arteries, effects that are reversed by the nitric oxide synthase inhibitor L-NAME and ODQ , an inhibitor of soluble guanylyl cyclase. In vivo, notoginsenoside Ft₁ (0.25, 2.5, and 25 mg/kg) promotes angiogenesis and decreases wound diameter in a mouse model of punched-hole ear injury. Notoginsenoside Ft₁ (1.25 mg/kg) decreases tail bleeding time and increases thrombus weight in a rat tail bleeding assay. Topical administration of notoginsenoside Ft₁ increases mRNA expression of the collagen expression, fibroblast proliferation, and scar formation genes COL1A1, COL3A1, TGF-β1, TGF-β3, and fibronectin, promotes neovascularization, reduces monocyte infiltration, and shortens wound closure time in a db/db mouse model of diabetic foot ulcers.

Notoginsenoside Ft1 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Notoginsenoside Ft1 manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Notoginsenoside Ft1 155683-00-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-05

Hebei Mojin Biotechnology Co., Ltd

Product: Notoginsenoside Ft1 155683-00-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-06-30

Shanghai Standard Technology Co., Ltd.

Product: Notoginsenoside Ft1 155683-00-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-03

155683-00-4, Notoginsenoside Ft1Related Search:

Notoginsenoside R2 20(R)-Notoginsenoside R2 Notoginseng triterpenes Panax notoginsenosides Notoginsenoside R1 Icariside I PICEATANNOL Gypenoside XLIX Saikosaponin G Palmatine epipinoresinol-4'-O-β-D-glucoside GYPENOSIDE-XVII Notoginsenoside Fa KAEMPFERITRIN Nobiletin ISOLIQUIRITIN Costunolide Forsythoside B

Notoginsenoside Ft1

(3beta,12beta,20R)-12,20-Dihydroxydammar-24-en-3-yl O-beta-D-xylopyranosyl-(1- 2)-O-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranoside

product/153944

β-D-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-

(2S,3R,4S,5R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol

155683-00-4

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract