2-Methyl-4-nitroimidazole
- Product Name
- 2-Methyl-4-nitroimidazole
- CAS No.
- 696-23-1
- Chemical Name
- 2-Methyl-4-nitroimidazole
- Synonyms
- menidazole;2-methyl-5-nitro-1h-imidazole;2-Methyl-4(5)-nitroimidazol;Tinidazole Related CoMpound A;RP-8532;RP 8532;L 581490;Ornidazole Impurity B;Tinidazole EP Impurity A;2-METHYL-5-NIROIMIDAZOLE
- CBNumber
- CB0259864
- Molecular Formula
- C4H5N3O2
- Formula Weight
- 127.1
- MOL File
- 696-23-1.mol
2-Methyl-4-nitroimidazole Property
- Melting point:
- 251-255 °C(lit.)
- Boiling point:
- 235.85°C (rough estimate)
- Density
- 1.4748 (rough estimate)
- refractive index
- 1.5000 (estimate)
- Flash point:
- 195℃
- storage temp.
- 2-8°C
- solubility
- DMSO (Sparingly), Methanol (Sparingly)
- form
- powder
- pka
- 8.87±0.10(Predicted)
- Appearance
- White to off-white Solid
- Water Solubility
- 3.01g/L(20 ºC)
- BRN
- 4032
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 696-23-1(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Imidazole, 2-methyl-4-nitro- (696-23-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Y0000899
- Product name
- Tinidazole impurity A
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 15 mg
- Price
- $156
- Updated
- 2025/07/31
- Product number
- Y0000087
- Product name
- Metronidazole impurity A
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 15 mg
- Price
- $236
- Updated
- 2025/07/31
- Product number
- BP244
- Product name
- 2-Methyl-5-nitroimidazole
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 50MG
- Price
- $212
- Updated
- 2025/07/31
- Product number
- 136255
- Product name
- 2-Methyl-4(5)-nitroimidazole
- Purity
- 99%
- Packaging
- 50g
- Price
- $52
- Updated
- 2025/07/31
- Product number
- 136255
- Product name
- 2-Methyl-4(5)-nitroimidazole
- Purity
- 99%
- Packaging
- 250g
- Price
- $173
- Updated
- 2025/07/31
2-Methyl-4-nitroimidazole Chemical Properties,Usage,Production
Chemical Properties
solid
Uses
Floconazole impurity.
Uses
2-Methyl-4(5)-nitroimidazole was used to study the mechanism of both the alkaline and acidic hydrolysis of tinidazole.
Definition
ChEBI: 2-Methyl-5-nitroimidazole is a C-nitro compound and a member of imidazoles.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Synthesis
13369-83-0
696-23-1
General procedure for the synthesis of 2-methyl-4-nitroimidazole from 4-iodo-2-methyl-5-nitro-1H-imidazole: (1) In a 5 mL microreaction flask, 50 mg of 4-bromo-2-methyl-5-nitroimidazole prepared in Example 1 was added, followed by the addition of 3 mL of methanol to dissolve it completely. Then, 5 mg of 10% palladium carbon (Pd/C) was added as a catalyst. The reaction flask was placed on a hydrogenation unit and high purity hydrogen was passed through, displacing it three times to ensure that the reaction system was free of oxygen. The reaction pressure was adjusted to 100 mmHg and the reaction was stirred at 25 °C for 30 h. The reaction pressure was adjusted to 100 mmHg. Upon completion of the reaction, the Pd/C catalyst was removed by centrifugation and the remaining liquid was concentrated by evaporation under reduced pressure to obtain the target product 2-methyl-5-nitroimidazole. The yield of this step was 47% by HPLC analysis.
References
[1] Patent: CN106674123, 2017, A. Location in patent: Paragraph 0039; 0040
2-Methyl-4-nitroimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Methyl-4-nitroimidazole manufacturers
- Product
- 2-methyl-4-nitroimidazole 696-23-1
- Price
- US $0.00/piece
- Min. Order
- 1piece
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2024-04-03
- Product
- 2-Methyl-4-nitroimidazole 696-23-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-Methyl-4(5)-nitroimidazole 696-23-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27