ChemicalBook > CAS DataBase List > TriMethyl(broModifluoroMethyl)silane

TriMethyl(broModifluoroMethyl)silane

Product Name: TriMethyl(broModifluoroMethyl)silane
CAS No.: 115262-01-6
Chemical Name: TriMethyl(broModifluoroMethyl)silane
Synonyms: (BroModifluoroMethyl)triMethylsilane;TMSCF2Br;(Bromodifluoromethyl);Difluorobromomethylsilane;TriMethyl(broModifluoroMethyl)silane;Bromodifluoro(trimethylsilyl)methane;Silane, (bromodifluoromethyl)trimethyl-;Trimethyl(bromodifluoromethyl)silane 97%;(Bromodifluoromethyl)trimethylsilane 98%;(Bromodifluoromethyl)trimethylsilane >
CBNumber: CB02611493
Molecular Formula: C4H9BrF2Si
Formula Weight: 203.1
MOL File: 115262-01-6.mol

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TriMethyl(broModifluoroMethyl)silane Property

Boiling point:: 108°C(lit.)
Density: 1.306
refractive index: n/D1.407
Flash point:: 46℃
storage temp.: -20°C
form: liquid
color: clear
InChI: InChI=1S/C4H9BrF2Si/c1-8(2,3)4(5,6)7/h1-3H3
InChIKey: WDZVWBWAUSUTTO-UHFFFAOYSA-N
SMILES: [Si](C(Br)(F)F)(C)(C)C
CAS DataBase Reference: 115262-01-6

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Safety

Risk Statements: 11
Safety Statements: 24/25
RIDADR: UN 1993C 3 / PGIII
TSCA: No
HazardClass: 3
PackingGroup: II
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 808601
Product name: (Bromodifluoromethyl)
Purity: 98%
Packaging: 1g
Price: $118
Updated: 2023/01/07

TCI Chemical

Product number: B4325
Product name: (Bromodifluoromethyl)trimethylsilane
Purity: >98.0%(GC)
Packaging: 1g
Price: $88
Updated: 2025/07/31

TCI Chemical

Product number: B4325
Product name: (Bromodifluoromethyl)trimethylsilane
Purity: >98.0%(GC)
Packaging: 5g
Price: $267
Updated: 2025/07/31

TRC

Product number: T895825
Product name: Trimethyl(bromodifluoromethyl)silane
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB60402
Product name: (Bromodifluoromethyl)trimethylsilane
Packaging: 500mg
Price: $60
Updated: 2021/12/16

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TriMethyl(broModifluoroMethyl)silane Chemical Properties,Usage,Production

Chemical Properties

Colorless transparent liquid, initial boiling point 108℃, relative density 1.31 g/cm³.

Uses

Novel difluorocarbene source for the efficient difluoromethylenation of alkenes/alkynes and difluoromethylation of O-, S-, and N-nucleophiles.

Uses

Trimethyl(bromodifluoromethyl)silane can be used as neuroactive steroids.

Uses

As reported by Hu and co-workers, (Bromodifluoromethyl)trimethylsilane is a highly useful reagent for the formation of difluoromethene-containing 3-membered rings and can also difluoromethylate heteroatoms with the assistance of alkaline bases, most effectively KOH.

Application

TriMethyl(broModifluoroMethyl)silane commonly can be used as a source for generating difluorocarbene, it is a general reagent with broad synthetic utility.
Can generate difluorocarbene under neutral/acidic/basic conditions in the presence/absence of water at low/high temperatures.
Can be used to prepare gem-difluorocyclopropan(e)nes, O-, S-, N-, and P-difluoromethylated compounds

Reactions

(1) Difluoromethylenation of TMSCN.

Ref. J. Org. Chem. 2012, 77, 5850?5855.
(2) Difluoromethylenation of benzyl and alkylzinc halides.

Ref. Org. Lett. 2013, 15, 917 – 919.
(3) Fluorination aminocarbonylation of aldehydes

Ref. Angew. Chem. Int. Ed. 2022, e202115467

General Description

(Bromodifluoromethyl)trimethylsilane (TMSCF₂Br) is commonly used as a source to generate dilfluorocarbene. TMSCF₃ (Ruppert–Prakash reagent) and BBr₃ undergoes fast halogen–exchange reaction to form MSCF₂Br.

References

[1]Angewandte Chemie International Edition.DOI :10.1002/anie.202283811
[2]The Journal of Organic Chemistry.DOI :10.1021/acs.orglett.2c02899

TriMethyl(broModifluoroMethyl)silane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from TriMethyl(broModifluoroMethyl)silane manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: TriMethyl(broModifluoroMethyl)silane 115262-01-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-07-08

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (Bromodifluoromethyl)trimethylsilane 115262-01-6
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-27

Henan Aochuang Chemical Co.,Ltd.

Product: TriMethyl(broModifluoroMethyl)silane 115262-01-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-09

115262-01-6, TriMethyl(broModifluoroMethyl)silaneRelated Search:

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(Bromodifluoromethyl)trimethylsilane 98%

TriMethyl(broModifluoroMethyl)silane

(BroModifluoroMethyl)triMethylsilane

Trimethyl(bromodifluoromethyl)silane 97%

Bromodifluoro(trimethylsilyl)methane

(Bromodifluoromethyl)

(Bromodifluoromethyl)trimethylsilane &gt

Silane, (bromodifluoromethyl)trimethyl-

Difluorobromomethylsilane

TriMethyl(broModifluoroMethyl)silane ISO 9001：2015 REACH

(Bromodifluoromethyl)trimethylsilane, 98+%

TMSCF2Br

115262-01-6

C4H9BrF2Si