ChemicalBook > CAS DataBase List > 3-BrB-PP1
3-BrB-PP1
- Product Name
- 3-BrB-PP1
- CAS No.
- 956025-99-3
- Chemical Name
- 3-BrB-PP1
- Synonyms
- 3-BrB-PP1;4-AMino-1-tert-butyl-3-(3-broMobenzyl)pyrazolo[3,4-d]pyriMidine;3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;3-[(3-bromophenyl)methyl]-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine;3-[(3-BroMophenyl)Methyl]-1-(1,1-diMethylethyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-bromophenyl)methyl]-1-(1,1-dimethylethyl)-
- CBNumber
- CB02621476
- Molecular Formula
- C16H18BrN5
- Formula Weight
- 360.25
- MOL File
- 956025-99-3.mol
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3-BrB-PP1 Property
- Melting point:
- 140-142°C
- Boiling point:
- 510.2±45.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 4.47±0.30(Predicted)
- form
- Solid
- color
- White to Pale Beige
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N-Bromosuccinimide Price
TRC
- Product number
- A602985
- Product name
- 4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
- Packaging
- 10mg
- Price
- $185
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 62852
- Product name
- 4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
- Packaging
- 10mg
- Price
- $650
- Updated
- 2021/12/16
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3-BrB-PP1 Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.
Definition
ChEBI: 3-BrB-PP1 is a member of the class of pyrazolopyrimidines that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 3-bromobenzyl substituents at positions 1 and 3 respectively. It is an ATP-competitive inhibitor of CDPK1 and AKT kinase. It has a role as an antiparasitic agent, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a pyrazolopyrimidine, a member of bromobenzenes and an aromatic amine.