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3-BrB-PP1

Product Name
3-BrB-PP1
CAS No.
956025-99-3
Chemical Name
3-BrB-PP1
Synonyms
3-BrB-PP1;4-AMino-1-tert-butyl-3-(3-broMobenzyl)pyrazolo[3,4-d]pyriMidine;3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;3-[(3-bromophenyl)methyl]-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine;3-[(3-BroMophenyl)Methyl]-1-(1,1-diMethylethyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-bromophenyl)methyl]-1-(1,1-dimethylethyl)-
CBNumber
CB02621476
Molecular Formula
C16H18BrN5
Formula Weight
360.25
MOL File
956025-99-3.mol
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3-BrB-PP1 Property

Melting point:
140-142°C
Boiling point:
510.2±45.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
4.47±0.30(Predicted)
form 
Solid
color 
White to Pale Beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A602985
Product name
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
Packaging
10mg
Price
$185
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
62852
Product name
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
Packaging
10mg
Price
$650
Updated
2021/12/16
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3-BrB-PP1 Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.

Definition

ChEBI: 3-BrB-PP1 is a member of the class of pyrazolopyrimidines that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 3-bromobenzyl substituents at positions 1 and 3 respectively. It is an ATP-competitive inhibitor of CDPK1 and AKT kinase. It has a role as an antiparasitic agent, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a pyrazolopyrimidine, a member of bromobenzenes and an aromatic amine.

3-BrB-PP1 Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BrB-PP1 Suppliers

J & K SCIENTIFIC LTD.
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956025-99-3, 3-BrB-PP1Related Search:


  • 3-[(3-BroMophenyl)Methyl]-1-(1,1-diMethylethyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
  • 3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • 3-BrB-PP1
  • 4-AMino-1-tert-butyl-3-(3-broMobenzyl)pyrazolo[3,4-d]pyriMidine
  • 3-[(3-bromophenyl)methyl]-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine
  • 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-bromophenyl)methyl]-1-(1,1-dimethylethyl)-
  • 956025-99-3
  • C16H18BrN5
  • Bases & Related Reagent
  • Heterocycles
  • Nucleotides
  • Protein Kinase Inhibitors and Activators