CMX 001

Product Name: CMX 001
CAS No.: 444805-28-1
Chemical Name: CMX 001
Synonyms: Brincidofovir (CMX001);CMX 001;HDP-CDV;CS-2275;HDP-HPMPC;HDP-cidofovir;Brincidofovir;CMX 001 - Bio-X ?;CMX001(Brincidofovir);Fampridine Impurity 23
CBNumber: CB02627690
Molecular Formula: C27H52N3O7P
Formula Weight: 561.69
MOL File: 444805-28-1.mol

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CMX 001 Property

Melting point:: > 177° C (dec.)
Boiling point:: 688.6±65.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli
form: Solid
pka: 2.40±0.10(Predicted)
color: White to Off-White
Stability:: Hygroscopic
InChIKey: WXJFKKQWPMNTIM-VWLOTQADSA-N
SMILES: P(CO[C@H](CO)CN1C(=O)N=C(N)C=C1)(=O)(O)OCCCOCCCCCCCCCCCCCCCC

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Safety

WGK Germany: WGK 3
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Carc. 2
Repr. 2
Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3155
Product name: Brincidofovir
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $87.1
Updated: 2026/04/30

Sigma-Aldrich

Product number: SML3155
Product name: Brincidofovir
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $351
Updated: 2026/04/30

Cayman Chemical

Product number: 35062
Product name: Brincidofovir
Purity: ≥98%
Packaging: 5mg
Price: $83
Updated: 2026/04/30

Cayman Chemical

Product number: 35062
Product name: Brincidofovir
Purity: ≥98%
Packaging: 10mg
Price: $158
Updated: 2026/04/30

Cayman Chemical

Product number: 35062
Product name: Brincidofovir
Purity: ≥98%
Packaging: 25mg
Price: $330
Updated: 2026/04/30

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CMX 001 Chemical Properties,Usage,Production

Uses

Brincidofovir is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells. Cytostatic, cytotoxic agent.

Biological Activity

cmx001 is a broad spectrum antiviral agent [1].cmx001 has been reported to be active in vitro against a broad range of viruses from all five families of dsdna viruses infecting human with ec50 values of 0.02μm, 0.0004μm, 17μm , 0.045μm and 0.07μm for adenovirus, herpesvirus, papillomavirus, polyomavirus and orthopoxvirus, respectively. in addition, cmx001 has been revealed to arrest disease progression by inhibiting viral dna replication and thereby reducing viral burden. apart from these, initial studies has been demonstrated the efficacy of cmx001 for pre-exposure and post-exposure prophylaxis in mouse, rabbit, cynomolgus monkeys and human [1].

in vivo

Brincidofovir (BCV) (20 mg/kg; p.o.; on days 1, 3, 5, 7, 10, 14, 17, 21, and 24) extends survival in immune-deficient BALB/c nu/nu mice following lethal challenge with IHD-J-Luc VACV^[3].

Animal Model:	BALB/c nu/nu mice (infected with IHD-J-Luc VACV)^[3]
Dosage:	20 mg/kg
Administration:	P.o.; on days 1, 3, 5, 7, 10, 14, 17, 21, and 24
Result:	On days 1, 3, and 5 maintained their weights initially but started to lose weight beginning on day 9 and succumbed between days 24 and 29 postchallenge.

References

[1]lanier r1, trost l, tippin t, lampert b, robertson a, foster s, rose m, painter w, o'mahony r, almond m, painter g.development of cmx001 for the treatment of poxvirus infections. viruses. 2010 dec; 2(12):2740-2762.

CMX 001 Preparation Products And Raw materials

Raw materials

Preparation Products

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CMX 001 Suppliers

Canada 1 CHINA 98 India 1 United States 6 USA 1 Global 107

Shenzhen Yaoyuan R&D Center Co., Ltd

Tel: 23284190 13421666688
Email: 664261110@qq.com
Country: China
ProdList: 60
Advantage: 58

Henan Yinuokai New Materials Co., Ltd

Tel: 15764055027 15764055027
Email: 15764055027@163.com
Country: China
ProdList: 542
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Beijing Ouhe Technology Co., Ltd

Tel: 13552068683 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 11780
Advantage: 60

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39999
Advantage: 60

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939; 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15781
Advantage: 55

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 89689
Advantage: 60

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View Lastest Price from CMX 001 manufacturers

shandong perfect biotechnology co.ltd

Product: Brincidofovir 444805-28-1
Price: US $0.00/g
Min. Order: 1g
Purity: 98% HPLC
Supply Ability: 1kg
Release date: 2023-08-02

R&D Scientific Inc.

Product: Brincidofovir 444805-28-1
Price: US $2500.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-11-12

444805-28-1, CMX 001Related Search:

Leflunomide Tolvaptan

Brincidofovir (CMX001)

Brincidofovir

CMX001(Brincidofovir)

CMX 001

HDP-cidofovir

Hexadecyloxypropyl-cidofovir

CMX 001 1-(hydroxymethyl)ethoxy]methyl]phosphonic acid mono[3-(hexadecyloxy)propyl] ester

(S)-[2-(4-amino-2-oxo-1,2-dihydro-1-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methylphosphonic acid 3-(hexadecyloxy)propyl monoester

[[(S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid mono[3-(hexadecyloxy)propyl] ester

CMX001;CMX 001;CMX-001;HDP-CIDOFOVIR;HEXADECYLOXYPROPYL-CIDOFOVIR

[(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-(3-hexadecoxypropoxy)phosphinic acid

HDP-CDV

HDP-CDV; HDP-HPMPC;CMX001; BRINCIDOFOVIR; HDP-CIDOFOVIR;CMX 001

HDP-HPMPC

Brincidofovir, CMX-001, HDP-CDV

CS-2275

Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, mono[3-(hexadecyloxy)propyl] ester

Brincidofovir (CMX001, HDP CDV, HDPCDV)

CMX 001,DNA,lipid-conjugated,Brincidofovir,CMX-001,HSV,Herpes simplex virus,Cytomegalovirus,prodrug,Inhibitor,Orthopoxvirus,viruses,antiviral,CMV,inhibit,infection

3-(Hexadecyloxy)propyl hydrogen ((((S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonate

({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)[3-(hexadecyloxy)propoxy]phosphinic acid

Fampridine Impurity 23

CMX 001 - Bio-X ?

3-(Hexadecyloxy)propyl (((S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxyprop-2-yl)oxy)methyl phosphate

444805-28-1

C27H52N3O7P