ChemicalBook > CAS DataBase List > FX-11
FX-11
- Product Name
- FX-11
- CAS No.
- 213971-34-7
- Chemical Name
- FX-11
- Synonyms
- DK664;FX-11;FX11,FX 11;LDHA Inhibitor FX11;FX-11 (LDHA inhibitor FX11);7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid;7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid;2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid;1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-
- CBNumber
- CB02627892
- Molecular Formula
- C22H22O4
- Formula Weight
- 350.41
- MOL File
- 213971-34-7.mol
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FX-11 Property
- Melting point:
- 183-184 °C
- Boiling point:
- 570.1±50.0 °C(Predicted)
- Density
- 1.260±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.70±0.40(Predicted)
- color
- Light Grey to Light Brown
- InChI
- InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26)
- InChIKey
- LVPYVYFMCKYFCZ-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=C2C(C=C(C)C(CC3=CC=CC=C3)=C2)=C(CCC)C(O)=C1O
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 427218
- Product name
- Lactate Dehydrogenase A Inhibitor, FX11 - Calbiochem
- Packaging
- 10mg
- Price
- $259
- Updated
- 2024/03/01
TRC
- Product number
- D453265
- Product name
- 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylicAcid
- Packaging
- 0.5mg
- Price
- $200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0006190
- Product name
- FX-11
- Purity
- 98.11%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0006190
- Product name
- FX-11
- Purity
- 98.11%
- Packaging
- 10mg
- Price
- $190
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD164039
- Product name
- 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid
- Packaging
- 500ug
- Price
- $500
- Updated
- 2021/12/16
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FX-11 Chemical Properties,Usage,Production
Description
FX-11 is an inhibitor of lactate dehydrogenase-A (LDH-A; Ki = 8 μM). It is selective for LDH-A over GAPDH (Ki = >300 μM). FX-11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX-11 (42 μg/animal, i.p.) reduces tumor volume in a P493-6 mouse xenograft model. It also reduces tumor weight in a BxPC-3 mouse xenograft model when administered at a dose of 2 mg/kg.
Uses
This compound is used in the synthesis of novel lactate dehydrogenase A inhibitors.This compound is suitable for lactate dehydrogenase (LDH) related research.
FX-11 Preparation Products And Raw materials
Raw materials
Preparation Products
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FX-11 Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
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View Lastest Price from FX-11 manufacturers
Hebei Yanxi Chemical Co., Ltd.
- Product
- 7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid 213971-34-7
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-04