FX-11

Product Name: FX-11
CAS No.: 213971-34-7
Chemical Name: FX-11
Synonyms: DK664;FX-11;FX11,FX 11;LDHA Inhibitor FX11;FX-11 (LDHA inhibitor FX11);7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid;7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid;2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid;1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-
CBNumber: CB02627892
Molecular Formula: C22H22O4
Formula Weight: 350.41
MOL File: 213971-34-7.mol

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FX-11 Property

Melting point:: 183-184 °C
Boiling point:: 570.1±50.0 °C(Predicted)
Density: 1.260±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 3.70±0.40(Predicted)
color: Light Grey to Light Brown
InChI: InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26)
InChIKey: LVPYVYFMCKYFCZ-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=C2C(C=C(C)C(CC3=CC=CC=C3)=C2)=C(CCC)C(O)=C1O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 427218
Product name: Lactate Dehydrogenase A Inhibitor, FX11 - Calbiochem
Packaging: 10mg
Price: $259
Updated: 2024/03/01

TRC

Product number: D453265
Product name: 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylicAcid
Packaging: 0.5mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-0006190
Product name: FX-11
Purity: 98.11%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0006190
Product name: FX-11
Purity: 98.11%
Packaging: 10mg
Price: $190
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD164039
Product name: 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid
Packaging: 500ug
Price: $500
Updated: 2021/12/16

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FX-11 Chemical Properties,Usage,Production

Description

FX-11 is an inhibitor of lactate dehydrogenase-A (LDH-A; Ki = 8 μM). It is selective for LDH-A over GAPDH (Ki = >300 μM). FX-11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX-11 (42 μg/animal, i.p.) reduces tumor volume in a P493-6 mouse xenograft model. It also reduces tumor weight in a BxPC-3 mouse xenograft model when administered at a dose of 2 mg/kg.

Uses

This compound is used in the synthesis of novel lactate dehydrogenase A inhibitors.This compound is suitable for lactate dehydrogenase (LDH) related research.

FX-11 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FX-11 manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid 213971-34-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-04

213971-34-7, FX-11Related Search:

FX-11

2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid

7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid

FX-11 (LDHA inhibitor FX11)

LDHA Inhibitor FX11

1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-

DK664

FX11,FX 11

7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid

213971-34-7

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