ChemicalBook > CAS DataBase List > 2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
- Product Name
- 2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
- CAS No.
- 71119-11-4
- Chemical Name
- 2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
- Synonyms
- Bucindolol;Bucindololum;Unii-E9uo06K7ce;Bucindololum [inn-latin];3-[2-[3-(o-Cyanophenoxy)-2-hydroxypropylamino]-2-methylpropyl]-1H-indole;2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE;2-(2-hydroxy-3-((2-(1h-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)benzonitr;2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile;Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-
- CBNumber
- CB0263148
- Molecular Formula
- C22H25N3O2
- Formula Weight
- 363.45
- MOL File
- 71119-11-4.mol
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2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Property
- Melting point:
- 125-127°
- Boiling point:
- 605.3±55.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.76±0.20(Predicted)
- color
- White to Off-White
- Stability:
- Hygroscopic
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21070
- Product name
- Bucindolol
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21070
- Product name
- Bucindolol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21070
- Product name
- Bucindolol
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $235
- Updated
- 2024/03/01
TRC
- Product number
- B689430
- Product name
- Bucindolol
- Packaging
- 25mg
- Price
- $180
- Updated
- 2021/12/16
Usbiological
- Product number
- 254833
- Product name
- Bucindolol
- Packaging
- 10mg
- Price
- $466
- Updated
- 2021/12/16
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2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Chemical Properties,Usage,Production
Uses
Antihypertensive.
Biological Activity
Non-selective β -adrenoceptor antagonist with additional α 1 -adrenoceptor blocking activity. K i values are 1.61, 1.20 and 68.9 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively. Also acts as a weak 5-HT 2A/2B antagonist. Displays vasodilatory and antihypertensive actions.
2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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