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2-Chloro-4-MethoxypyriMidin-5-aMine

Product Name
2-Chloro-4-MethoxypyriMidin-5-aMine
CAS No.
96833-41-9
Chemical Name
2-Chloro-4-MethoxypyriMidin-5-aMine
Synonyms
2-CHLORO-4-METHOXYPYRIMIDIN-5-AMIN;2-Chloro-4-methoxy-5-pyrimidinamine;2-Chloro-4-MethoxypyriMidin-5-aMine;2-chloro-4-methoxy-5-Aminopyrimidine;5-Amino-2-chloro-4-methoxypyrimidine;5-Pyrimidinamine, 2-chloro-4-methoxy-;2-Chloro-4-methoxypyrimidin-5-ylamine;2-chloro-4-methoxypyrimidine-5-ylamine
CBNumber
CB02638610
Molecular Formula
C5H6ClN3O
Formula Weight
159.57
MOL File
96833-41-9.mol
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2-Chloro-4-MethoxypyriMidin-5-aMine Property

Boiling point:
349.6±22.0 °C(Predicted)
Density 
1.398±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
1.36±0.29(Predicted)
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
5514AJ
Product name
2-Chloro-4-methoxypyrimidin-5-amine
Packaging
5g
Price
$558
Updated
2021/12/16
AK Scientific
Product number
5514AJ
Product name
2-Chloro-4-methoxypyrimidin-5-amine
Packaging
25g
Price
$2576
Updated
2021/12/16
Alichem
Product number
96833419
Product name
5-Amino-2-chloro-4-methoxypyrimidine
Packaging
5g
Price
$570.93
Updated
2021/12/16
Chemenu
Product number
CM256026
Product name
2-Chloro-4-methoxypyrimidin-5-amine
Purity
97%
Packaging
10g
Price
$664
Updated
2021/12/16
Azepine
Product number
AZ0001-0591
Product name
2-Chloro-4-methoxypyrimidin-5-amine
Purity
98
Packaging
5G
Price
$790
Updated
2021/12/16
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2-Chloro-4-MethoxypyriMidin-5-aMine Chemical Properties,Usage,Production

Synthesis

5177-27-5

124-41-4

96833-41-9

General procedure for the preparation of 2-chloro-4-methoxypyrimidin-5-amine: sodium methanolate (0.5 M solution in methanol, 3.7 mL, 1.829 mmol) was slowly added to a solution of 2,4-dichloropyrimidin-5-amine (0.2 g, 1.220 mmol) in methanol (2.5 mL). The reaction mixture was stirred at room temperature for 1.5 hours. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate and quenched with deionized water. The organic and aqueous layers were separated and the aqueous layer was further extracted with ethyl acetate. All organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the title compound 2-chloro-4-methoxypyrimidin-5-amine as a brown solid (177 mg, 91% yield). The product was characterized by 1H NMR (500 MHz, CDCl3): δ 3.93 (s, 3H), 5.31 (br s, 2H), 7.73 (s, 1H).LC-MS analysis (Method B, ESI positive ion mode) showed a retention time t R of 1.6 min and a molecular ion peak m/z of 160 [M + H]+ .

References

[1] Patent: US2013/345181, 2013, A1. Location in patent: Paragraph 0785
[2] Patent: WO2014/184234, 2014, A1. Location in patent: Page/Page column 71; 72
[3] Patent: WO2014/191632, 2014, A1. Location in patent: Page/Page column 56

2-Chloro-4-MethoxypyriMidin-5-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-4-MethoxypyriMidin-5-aMine Suppliers

China 39 India 1 United Kingdom 1 United States 4 Global 45
Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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sales@accelachem.com
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China
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
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China
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Shanghai Synthfine Chemical Co.,Ltd
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15921303235
Fax
QQ489466966
Email
sales@synthfine.com
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China
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Letopharm Limited
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+86-21-5106 2861
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
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+86-21-61629029
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product02@bidepharm.com
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Nantong Bosu Pharmaceutical Technology Co., Ltd.
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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Guangdong wengjiang Chemical Reagent Co., Ltd.
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0751-2886750 13927877953
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0751-2886750
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China
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13305
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Nanijing m&m biotechnology Co. ,Ltd.
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025-87782433 18021532344
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1345332203@qq.com
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96833-41-9, 2-Chloro-4-MethoxypyriMidin-5-aMineRelated Search:


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  • 2-CHLORO-4-METHOXYPYRIMIDIN-5-AMIN
  • 2-chloro-4-methoxypyrimidine-5-ylamine
  • 2-chloro-4-methoxy-5-Aminopyrimidine
  • 2-Chloro-4-methoxypyrimidin-5-ylamine
  • 5-Amino-2-chloro-4-methoxypyrimidine
  • 5-Pyrimidinamine, 2-chloro-4-methoxy-
  • 2-Chloro-4-methoxy-5-pyrimidinamine
  • 96833-41-9