5-IODO-1,3-DIMETHYLURACIL Property

Melting point:

225 °C (dec.)(lit.)

Boiling point:

261.3±43.0 °C(Predicted)

Density 

2.04±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

solubility 

DMSO: soluble10mg/mL(lit.)

pka

-3.54±0.40(Predicted)

Sensitive 

Light Sensitive

CAS DataBase Reference

40738-83-8

Safety

Hazard Codes 

Xn

Risk Statements 

20/21/22-42/43-63

Safety Statements 

22-26-36/37/39-45

WGK Germany 

3

HS Code 

29335990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

5-IODO-1,3-DIMETHYLURACIL Chemical Properties,Usage,Production

Uses

5-Iodo-1,3-dimethyluracil may be used for the synthesis of N-[2-[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)thio]-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)yl]methanesulfonamide.

General Description

The effect of 5-iodo-1,3-dimethyluracil on the incorporation of [¹²⁵I] 5-iodo-2′-deoxyuridine [¹²⁵I radiolabelled IdUrd] in DNA of cancer cells has been studied. Synthesis of 5-iodo-1,3-dimethyluracil from aromatic organomercurials; 5-(acetoxymercurio)-1,3-dimethyluracil or 5,5′-mercuriobis(1,3-dimethyluracil) has been reported.