1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
- Product Name
- 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
- CAS No.
- 862574-87-6
- Chemical Name
- 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
- Synonyms
- EOS-61001;Lummakato impurities1;Thiocoraline Impurity14;1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile;1-(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbo...;1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropan-carbonitrile;Cyclopropanecarbonitrile, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-;1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE-1-CARBONITRILE;1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile;1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonitrile
- CBNumber
- CB02658232
- Molecular Formula
- C11H7F2NO2
- Formula Weight
- 223.18
- MOL File
- 862574-87-6.mol
1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile Property
- Boiling point:
- 298.7±40.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D445858
- Product name
- 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- D445858
- Product name
- 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-M2544
- Product name
- Cyclopropanecarbonitrile,1-(2,2-difluoro-1,3-benzodioxol-5-yl)-
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- 3003AH
- Product name
- 1-(2,2-Difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarbonitrile
- Packaging
- 5g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 4H37-3-29
- Product name
- 1-(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonitrile
- Purity
- 97.0%
- Packaging
- 250mg
- Price
- $190
- Updated
- 2021/12/16
1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile Chemical Properties,Usage,Production
Synthesis
68119-31-3
107-04-0
862574-87-6
(2,2-Difluoro-1,3-benzodioxol-5-yl)-acetonitrile (1.0 eq.) was used as a raw material, mixed with 50 wt% aqueous KOH (5.0 eq.), 1-bromo-2-chloroethane (1.5 eq.) and tetrabutylammonium bromide (0.02 eq.) and heated to react for 1 hr at 70 °C. After completion of the reaction, the reaction mixture was cooled and subsequently treated with methyl tertiary butyl ether (MTBE) and water for extraction. The organic phase was washed sequentially with water and brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent to afford the target product 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonitrile.
References
[1] Patent: WO2009/73757, 2009, A1. Location in patent: Page/Page column 21
[2] Patent: WO2010/37066, 2010, A2. Location in patent: Page/Page column 12; 26
[3] Patent: US2016/324788, 2016, A1. Location in patent: Paragraph 0361; 0362
[4] Patent: WO2009/76142, 2009, A2. Location in patent: Page/Page column 51
[5] Patent: US2007/244159, 2007, A1. Location in patent: Page/Page column 79
1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile manufacturers
- Product
- 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile 862574-87-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-06
- Product
- 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile 862574-87-6
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carbonitrile 862574-87-6
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg,100kg
- Release date
- 2020-01-09