Lumazine
- Product Name
- Lumazine
- CAS No.
- 487-21-8
- Chemical Name
- Lumazine
- Synonyms
- pteridine-2,4-diol;2,4-DIHYDROXYPTERIDINE;Lumazin;LUMAZINE;NSC 41801;Lumazine>Lumazine,98%;LUMAZINE 99+%;Pteridine-2,4-;2,4-PTERIDINEDIOL
- CBNumber
- CB0271293
- Molecular Formula
- C6H4N4O2
- Formula Weight
- 164.12
- MOL File
- 487-21-8.mol
Lumazine Property
- Melting point:
- 300 °C
- Boiling point:
- 291.56°C (rough estimate)
- Density
- 1.5129 (rough estimate)
- refractive index
- 1.6900 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly)
- pka
- pK1:<1.3;pK2:7.92 (25°C)
- form
- crystalline
- color
- yellow
- Water Solubility
- 0.125 g/100 mL (25 ºC)
- Merck
- 14,5596
- BRN
- 157503
- CAS DataBase Reference
- 487-21-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Lumazine(487-21-8)
- EPA Substance Registry System
- Lumazine (487-21-8)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- UO3416000
- TSCA
- Yes
- HS Code
- 29335995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- L0086
- Product name
- Lumazine
- Purity
- >99.0%(T)
- Packaging
- 1g
- Price
- $117
- Updated
- 2025/07/31
- Product number
- L0086
- Product name
- Lumazine
- Purity
- >99.0%(T)
- Packaging
- 5g
- Price
- $377
- Updated
- 2025/07/31
- Product number
- L473800
- Product name
- Lumazine
- Packaging
- 10g
- Price
- $845
- Updated
- 2021/12/16
- Product number
- PRO0003604
- Product name
- LUMAZINE
- Purity
- 95.00%
- Packaging
- 10G
- Price
- $1177.75
- Updated
- 2021/12/16
- Product number
- FP52412
- Product name
- 2,4-(1H,3H)-Pteridinedione
- Packaging
- 100g
- Price
- $1250
- Updated
- 2021/12/16
Lumazine Chemical Properties,Usage,Production
Chemical Properties
LIGHT YELLOW TO OCHRE POWDER
Uses
Lumazine is a new MALDI matrix for complex (phospho)lipid mixtures analysis.
Definition
ChEBI: A 2,4-dihydroxypteridine.
Synthesis
25911-65-3
124-38-9
487-21-8
The general procedure for the synthesis of pteridine-2,4-dione from 3-aminopyrazine-2-carbonitrile (1 mmol, 120 mg) and carbon dioxide was as follows: 3-aminopyrazine-2-carbonitrile (Compound 1d) and the ionic liquid [HDBN+][TFE-] (6 mmol, 1.35 g) were added to a 10 mL round bottom flask. The reaction mixture was heated to 90 °C under carbon dioxide atmosphere for 20 hours. After completion of the reaction, the system was cooled to room temperature and the pH was adjusted to neutral by adding saturated aqueous NH4Cl solution. The reaction mixture was extracted with dichloromethane (20 mL x 3), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure. Purification by silica gel column chromatography (eluent ratio of dichloromethane:methanol=15:1) afforded a light yellow solid pteridine-2,4-dione (compound 2d, 141 mg) in 86% yield.
Purification Methods
Crystallise the dione from water. It has also been purified as for pterin below. [Dallacker & Steiner Justus Liebigs Ann Chem 660 98 1962, Beilstein 26 III/IV 2489.]
References
[1] Patent: CN107698587, 2018, A. Location in patent: Paragraph 0039; 0040; 0041
Lumazine Preparation Products And Raw materials
Raw materials
Preparation Products
Lumazine Suppliers
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- 4006356688 18621169109
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- 86-21-61259102
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- China
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View Lastest Price from Lumazine manufacturers
- Product
- Lumazine 487-21-8
- Price
- US $31.00-19.00/kg
- Min. Order
- 1kg
- Purity
- 99.60%
- Supply Ability
- 20tons
- Release date
- 2023-04-28
- Product
- Lumazine 487-21-8
- Price
- US $25.00/kg
- Min. Order
- 1kg
- Purity
- 99.96%
- Supply Ability
- 500kg
- Release date
- 2023-04-28
- Product
- Lumazine 487-21-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11