ChemicalBook > CAS DataBase List > Lumazine

Lumazine

Product Name: Lumazine
CAS No.: 487-21-8
Chemical Name: Lumazine
Synonyms: pteridine-2,4-diol;2,4-DIHYDROXYPTERIDINE;Lumazin;LUMAZINE;NSC 41801;Lumazine>Lumazine,98%;LUMAZINE 99+%;Pteridine-2,4-;2,4-PTERIDINEDIOL
CBNumber: CB0271293
Molecular Formula: C6H4N4O2
Formula Weight: 164.12
MOL File: 487-21-8.mol

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Lumazine Property

Melting point:: 300 °C
Boiling point:: 291.56°C (rough estimate)
Density: 1.5129 (rough estimate)
refractive index: 1.6900 (estimate)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly)
pka: pK1:<1.3;pK2:7.92 (25°C)
form: crystalline
color: yellow
Water Solubility: 0.125 g/100 mL (25 ºC)
Merck: 14,5596
BRN: 157503
CAS DataBase Reference: 487-21-8(CAS DataBase Reference)
NIST Chemistry Reference: Lumazine(487-21-8)
EPA Substance Registry System: Lumazine (487-21-8)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: UO3416000
TSCA: Yes
HS Code: 29335995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: L0086
Product name: Lumazine
Purity: >99.0%(T)
Packaging: 1g
Price: $117
Updated: 2025/07/31

TCI Chemical

Product number: L0086
Product name: Lumazine
Purity: >99.0%(T)
Packaging: 5g
Price: $377
Updated: 2025/07/31

TRC

Product number: L473800
Product name: Lumazine
Packaging: 10g
Price: $845
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PRO0003604
Product name: LUMAZINE
Purity: 95.00%
Packaging: 10G
Price: $1177.75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP52412
Product name: 2,4-(1H,3H)-Pteridinedione
Packaging: 100g
Price: $1250
Updated: 2021/12/16

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Lumazine Chemical Properties,Usage,Production

Chemical Properties

LIGHT YELLOW TO OCHRE POWDER

Uses

Lumazine is a new MALDI matrix for complex (phospho)lipid mixtures analysis.

Definition

ChEBI: A 2,4-dihydroxypteridine.

Synthesis

25911-65-3

124-38-9

487-21-8

The general procedure for the synthesis of pteridine-2,4-dione from 3-aminopyrazine-2-carbonitrile (1 mmol, 120 mg) and carbon dioxide was as follows: 3-aminopyrazine-2-carbonitrile (Compound 1d) and the ionic liquid [HDBN+][TFE-] (6 mmol, 1.35 g) were added to a 10 mL round bottom flask. The reaction mixture was heated to 90 °C under carbon dioxide atmosphere for 20 hours. After completion of the reaction, the system was cooled to room temperature and the pH was adjusted to neutral by adding saturated aqueous NH4Cl solution. The reaction mixture was extracted with dichloromethane (20 mL x 3), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure. Purification by silica gel column chromatography (eluent ratio of dichloromethane:methanol=15:1) afforded a light yellow solid pteridine-2,4-dione (compound 2d, 141 mg) in 86% yield.

Purification Methods

Crystallise the dione from water. It has also been purified as for pterin below. [Dallacker & Steiner Justus Liebigs Ann Chem 660 98 1962, Beilstein 26 III/IV 2489.]

References

[1] Patent: CN107698587, 2018, A. Location in patent: Paragraph 0039; 0040; 0041

Lumazine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Lumazine manufacturers

Wuhan Boyuan Import & Export Co., LTD

Product: Lumazine 487-21-8
Price: US $31.00-19.00/kg
Min. Order: 1kg
Purity: 99.60%
Supply Ability: 20tons
Release date: 2023-04-28

Wuhan Boyuan Import & Export Co., LTD

Product: Lumazine 487-21-8
Price: US $25.00/kg
Min. Order: 1kg
Purity: 99.96%
Supply Ability: 500kg
Release date: 2023-04-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: Lumazine 487-21-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

487-21-8, LumazineRelated Search:

1,3-Dihydroxyacetone Aminophylline Butylated Hydroxytoluene Triamterene 1-Hydroxyethylidene-1,1-diphosphonic acid Theophylline 3-Diethylaminophenol Diprophylline Triclosan Doxofylline Chrysin LUMICHROME ALLOXAZINE XANTHOPTERIN MONOHYDRATE Lumazine, 7-benzyl-6-hydroxy-3-methyl-1-o-tolyl- (6CI) Lumazine, 5,6,7,8-tetrahydro-3,6,7-trimethyl- (8CI) 4-HYDROXYPTERIDINE Lumazine

2,4-PTERIDINEDIOL

2,4-HYDROXYPTERIDINE

2,4(1H,3H)-PTERIDINEDIONE

2,4-DIHYDROXYPTERIDINE

2,4-DIHYDROCYPTERIDINE

2,4(3H,8H)-Pteridinedione

LUMAZINE

Pteridine-2,4-

1,2,3,4-tetrahydropteridine-2,4-dione

2,4-diol monohydrate

Lumazin

lumazine monohydrate

pteridine-2,4-diol monohydrate

2,4-Dihydrocypteridin

LUMAZINE 99+%

2,4-DIHYDROXYPTERIDINE 98+%

2,4(1H,3H)-Pteridinedione, 2,4-Dihydroxypteridine, 2,4-Pteridinediol

Pteridine-2,4-dione

Pteridine-2,4(3H,8H)-dione

Lumazine,98%

pteridine-2,4-diol

NSC 41801

2,4-Dihydroxypteridine 2,4-Pteridinediol

Lumazine&gt

Lumazine 2,4-pteridinediol

Pteridine-2,4(1H,3H)-dione, 10 mM in DMSO

487-21-8

55-58-9

C6H4N4O2

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