FR901465

Product Name: FR901465
CAS No.: 146478-73-1
Chemical Name: FR901465
Synonyms: WB 2663C;FR901465;DQTXAXNYLWRTPB-NTVXLVODSA-N;(2S,3Z)-4-{[(2R,3R,5S,6S)-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]penta-2,4-dien-1-yl]oxan-3-yl]carbamoyl}but-3-en-2-yl acetate;2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)-
CBNumber: CB02716235
Molecular Formula: C27H41NO9
Formula Weight: 523.62
MOL File: 146478-73-1.mol

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FR901465 Property

Boiling point:: 735.6±60.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
pka: 12.43±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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FR901465 Chemical Properties,Usage,Production

Uses

FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1].

Definition

ChEBI: A spiro-epoxide with potent cytotoxic activity against human tumour cells. It is isolated from Pseudomonas sp. no.2663.

References

[1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. DOI:10.7164/antibiotics.49.1204
[2] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. DOI:10.7164/antibiotics.50.96
[3] Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT

FR901465 Preparation Products And Raw materials

Raw materials

Preparation Products

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FR901465 Suppliers

China 17 United States 2 Global 19

Nanjing Sunlida Biological Technology Co., Ltd.

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146478-73-1, FR901465Related Search:

FR901463 FR901464

FR901465

DQTXAXNYLWRTPB-NTVXLVODSA-N

2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)-

WB 2663C

(2S,3Z)-4-{[(2R,3R,5S,6S)-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]penta-2,4-dien-1-yl]oxan-3-yl]carbamoyl}but-3-en-2-yl acetate

146478-73-1