ChemicalBook > CAS DataBase List > FR901463
FR901463
- Product Name
- FR901463
- CAS No.
- 146478-74-2
- Chemical Name
- FR901463
- Synonyms
- FR901463;WB 2663A;F 901463;RONUKPQOBQKEHX-QHYZBLTGSA-N;(2S,3Z)-4-{[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(2R,3R,4S,6S)-4-(chloromethyl)-3,4,6-trihydroxy-6-methyloxan-2-yl]-3-methylpenta-2,4-dien-1-yl]-2,5-dimethyloxan-3-yl]carbamoyl}but-3-en-2-yl acetate
- CBNumber
- CB72716234
- Molecular Formula
- C27H42ClNO8
- Formula Weight
- 544.07728
- MOL File
- 146478-74-2.mol
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FR901463 Chemical Properties,Usage,Production
Uses
FR901463 is a potent anti-cancer agent and can be used for cancer research. FR901463 enhances the transcriptional activity of the promoter of SV40 DNA virus[1].
Definition
ChEBI: A cyclic hemiketal isolated from the fermentation broth of Pseudomonas sp.no.2663. It displays potent cytotoxic activity against human tumour cells.
References
[1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1996 Dec;49(12):1196-203. DOI:10.7164/antibiotics.49.1196
FR901463 Preparation Products And Raw materials
Raw materials
Preparation Products
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