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Sofosbuvir IMpurity B

Product Name
Sofosbuvir IMpurity B
CAS No.
1496552-51-2
Chemical Name
Sofosbuvir IMpurity B
Synonyms
Sofosbuvir IMpurity B;Sofosbuvir impurity K;Sofosbuvir Chloro Analog;Sofosbuvir Chloro Analogue;sofosbuvir impurity Y008005-K;Sofosbuvir Ph.Int Impurity B(Chloro Sofosbuvir);L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;(2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
CBNumber
CB02716563
Molecular Formula
C22H29ClN3O9P
Formula Weight
545.91
MOL File
1496552-51-2.mol
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Sofosbuvir IMpurity B Property

Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
9.39±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C382095
Product name
ChloroSofosbuvir
Packaging
0.5mg
Price
$210
Updated
2021/12/16
TRC
Product number
C382095
Product name
ChloroSofosbuvir
Packaging
5mg
Price
$1680
Updated
2021/12/16
ChemScene
Product number
CS-7854
Product name
SofosbuvirimpurityK
Packaging
1mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-7854
Product name
SofosbuvirimpurityK
Packaging
5mg
Price
$4200
Updated
2021/12/16
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Sofosbuvir IMpurity B Chemical Properties,Usage,Production

Uses

Chloro Sofosbuvir is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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Sofosbuvir IMpurity B Suppliers

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View Lastest Price from Sofosbuvir IMpurity B manufacturers

Henan Fengda Chemical Co., Ltd
Product
Sofosbuvir IMpurity B 1496552-51-2
Price
US $8.00-2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-25

1496552-51-2, Sofosbuvir IMpurity BRelated Search:


  • Sofosbuvir IMpurity B
  • (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • Sofosbuvir impurity K
  • (2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • sofosbuvir impurity Y008005-K
  • Sofosbuvir Chloro Analog
  • L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
  • Sofosbuvir Chloro Analogue
  • ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
  • Sofosbuvir Ph.Int Impurity B(Chloro Sofosbuvir)
  • 1496552-51-2