ChemicalBook > CAS DataBase List > (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
Uses- Product Name
- (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
- CAS No.
- 1190363-46-2
- Chemical Name
- (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
- Synonyms
- 5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-, (6S,9R)-;EOS-60325;Ramazepam Impurity 8;BMS-846372 Impurity 1;Rimegepant Impurity 8;Rimegepant Impurity 14;(6S,9R)-6-(2,3-Difluoroph;5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-;9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one hydrochloride;ERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
- CBNumber
- CB02717474
- Molecular Formula
- C25H33F2NO2Si
- Formula Weight
- 445.62
- MOL File
- 1190363-46-2.mol
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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Property
- Boiling point:
- 477.5±45.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- pka
- 2.97±0.60(Predicted)
- InChIKey
- AIVVBBARCYSYDU-SIKLNZKXSA-N
- SMILES
- C12[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CC[C@@H](C3=CC=CC(F)=C3F)C(=O)C1=CC=CN=2
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- ORS0014114
- Product name
- (6S,9R)-6-(2,3-DIFLUOROPHENYL)-9-((TRIISOPROPYLSILYL)OXY)-6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDIN-5-ONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.36
- Updated
- 2021/12/16
Chemenu
- Product number
- CM328793
- Product name
- 6-(2,3-difluorophenyl)-9-tri(propan-2-yl)silyloxy-6,7,8,9-tetrahydrocyclohepta[b]pyridin-5-one
- Purity
- 95+%
- Packaging
- 1000g
- Price
- $147200
- Updated
- 2021/12/16
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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Chemical Properties,Usage,Production
Uses
(6S,9R)-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrien[B]pyridin-5-one is a pharmaceutical chemical intermediate that can be used in the production of the drug molecule Remegapan.
Chemical Properties
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrieno[B]pyridin-5-one is a cycloheptanone-pyridinium organic compound with a reactive hydroxyl reactive group protected by a silyl unit in its structure, which can be hydrolyzed to remove the silyl protecting group under acidic conditions. In addition, its structure contains a carbonyl α-carbon atom chiral center, which is sensitive to alkalis and is prone to undergo enolic reciprocal isomerism under the action of bases leading to the disappearance of its chirality.
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Preparation Products And Raw materials
Raw materials
Preparation Products
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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Suppliers
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View Lastest Price from (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one 1190363-46-2
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-13
Hangzhou ICH Biofarm Co., Ltd
- Product
- 5H-?Cyclohepta[b]?pyridin-?5-?one, 6-?(2,?3-?difluorophenyl)?-?6,?7,?8,?9-?tetrahydro-?9-?[[tris(1-?methylethyl)?silyl]?oxy]?-?, (6S,?9R)?- 1190363-46-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2023-06-28
1190363-46-2, (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-oneRelated Search:
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((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone