ChemicalBook > CAS DataBase List > 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)

Product Name: 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)
CAS No.: 474922-20-8
Chemical Name: 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)
Synonyms: DSPE-PEG2000-COOH;DSPE-PEG-2K-CH2COOH;DSPE-PEG(2000) Carboxylic Acid;1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt);1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt);Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-(carboxymethoxy)-, ammonium salt (1:1)
CBNumber: CB02720544
Molecular Formula: C134H267N2O57P
Formula Weight: 0
MOL File: 474922-20-8.mol

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1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) Property

solubility: Ethanol: Sparingly soluble: 1-10 mg/ml
InChIKey: MFOLYTNLQCGGBD-UHFFFAOYSA-N
SMILES: C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)O{-}CC{+n}OCC(=O)O.N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22719
Product name: DSPE-PEG-CH2COOH,MW2K
Packaging: 100mg
Price: $180
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIP0000728
Product name: DSPE-PEG(2000) CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $550
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIP0000728
Product name: DSPE-PEG(2000) CARBOXYLIC ACID
Purity: 95.00%
Packaging: 500MG
Price: $5040
Updated: 2021/12/16

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1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) Chemical Properties,Usage,Production

Description

DSPE-PEG-CH2COOH, MW 2,000 is a PEG polymer with DSPE and carboxylic acid end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The -COOH group can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide bond.

Uses

DSPE-PEG-Carboxylic Acid is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted agents and genes[1].

References

[1] Su H, et, al. A brightly red emissive AIEgen and its antibody conjugated nanoparticles for cancer cell targeting imaging. Materials Chemistry Frontiers. Issue 10, 2022.
[2] XUEMING LI . Targeted delivery of doxorubicin using stealth liposomes modified with transferrin[J]. International Journal of Pharmaceutics, 2009, 373 1: Pages 116-123. DOI: 10.1016/j.ijpharm.2009.01.023
[3] LINGWEI MENG . Improving glioblastoma therapeutic outcomes via doxorubicin-loaded nanomicelles modified with borneol[J]. International Journal of Pharmaceutics, 2019, 567: Article 118485. DOI: 10.1016/j.ijpharm.2019.118485

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) Preparation Products And Raw materials

Raw materials

Preparation Products

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474922-20-8, 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)Related Search:

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine DSPE-PEG2000-SH 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT) DPPE-MPEG 5000 DSPE-PEG2000-FITC DSPE-PEG-Mal N-PALMITOYL-D-SPHINGOMYELIN L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE MPEG-2000-DSPE 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[PDP(polyethylene glycol)-2000] (aMMoniuM salt) 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[cyanur(polyethylene glycol)-2000] (aMMoniuM salt) Folic acid PEG DSPE DSPE-PEG-NH2

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)

DSPE-PEG(2000) Carboxylic Acid

DSPE-PEG2000-COOH

DSPE-PEG-2K-CH2COOH

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt)

Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-(carboxymethoxy)-, ammonium salt (1:1)

474922-20-8