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Propanoic acid, 2-cyano-

Product Name
Propanoic acid, 2-cyano-
CAS No.
632-07-5
Chemical Name
Propanoic acid, 2-cyano-
Synonyms
NSC 528442;Propanoic acid, 2-cyano-;alpha-Cyanopropionic acid;2-cyano-2-methylacetic acid
CBNumber
CB02739090
Molecular Formula
C4H5NO2
Formula Weight
99.09
MOL File
632-07-5.mol
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Propanoic acid, 2-cyano- Property

Melting point:
35°C
Boiling point:
185.54°C (rough estimate)
Density 
1.1400
refractive index 
1.4166 (estimate)
storage temp. 
2-8°C
form 
liquid
pka
2.57±0.10(Predicted)
color 
Pale yellow
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
7752BA
Product name
2-Cyanopropanoicacid
Packaging
250mg
Price
$494
Updated
2021/12/16
AK Scientific
Product number
7752BA
Product name
2-Cyanopropanoicacid
Packaging
5g
Price
$1464
Updated
2021/12/16
AK Scientific
Product number
7752BA
Product name
2-Cyanopropanoicacid
Packaging
10g
Price
$2560
Updated
2021/12/16
Ambeed
Product number
A134730
Product name
2-Cyanopropanoicacid
Purity
97%
Packaging
5g
Price
$737
Updated
2021/12/16
Crysdot
Product number
CD13008003
Product name
2-Cyanopropanoicacid
Purity
97%
Packaging
5g
Price
$743
Updated
2021/12/16
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Propanoic acid, 2-cyano- Chemical Properties,Usage,Production

Synthesis

1572-99-2

632-07-5

General procedure for the synthesis of 2-cyanopropionic acid from ethyl 2-cyanopropionate: ethyl 2-cyanopropionate (1.0 g, 7.87 mmol), methanol (4 mL), and water (4 mL) were added to a reaction flask. After cooling the reaction mixture to 0°C, potassium hydroxide (882 mg, 16 mmol) was slowly added. Subsequently, the reaction system was warmed to 40 °C with continuous stirring for 2 hours. Upon completion of the reaction, methanol was removed by concentration under reduced pressure and the pH was adjusted to 5 with 1 N hydrochloric acid. extraction was carried out with ethyl acetate (50 mL x 2) and the organic phases were combined. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-cyanopropionic acid (660 mg, 85% yield) as a purple oil. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 13.59 (br, 1H), 4.03 (q, J=7.2 Hz, 1H), 1.41 (d, J=7.2 Hz, 3H).

References

[1] Angewandte Chemie - International Edition, 2015, vol. 54, # 33, p. 9668 - 9672
[2] Angew. Chem., 2015, vol. 127, # 33, p. 9804 - 9808,5
[3] Angewandte Chemie - International Edition, 2008, vol. 47, # 18, p. 3381 - 3384
[4] Patent: US2018/282328, 2018, A1. Location in patent: Paragraph 0859; 0860
[5] Chemische Berichte, 1930, vol. 63, p. 2385

Propanoic acid, 2-cyano- Preparation Products And Raw materials

Raw materials

Preparation Products

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Propanoic acid, 2-cyano- Suppliers

Beijing Ouhe Technology Co., Ltd
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010-010-82967028 13522913783
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China
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12000
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60
Bide Pharmatech Ltd.
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China
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Mashilabs (Shanghai) Co.,Ltd.
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19916721580
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Changzhou Hopschain Chemical Co.,Ltd.
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Capot Chemical Co.,Ltd.
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Aikon International Limited
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Cool Pharm, Ltd
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Hefei TNJ Chemical Industry Co.,Ltd.
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Chongqing Chemdad Co., Ltd
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China
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View Lastest Price from Propanoic acid, 2-cyano- manufacturers

Career Henan Chemical Co
Product
Propanoic acid, 2-cyano- 632-07-5
Price
US $8.00/KG
Min. Order
1KG
Purity
>98% HPLC
Supply Ability
20 tons
Release date
2020-02-17

632-07-5, Propanoic acid, 2-cyano-Related Search:


  • Propanoic acid, 2-cyano-
  • alpha-Cyanopropionic acid
  • NSC 528442
  • 2-cyano-2-methylacetic acid
  • 632-07-5