1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride

Product Name: 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
CAS No.: 455311-98-5
Chemical Name: 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
Synonyms: BEPP monohydrochloride;1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
CBNumber: CB02755821
Molecular Formula: C23H24ClN3O2
Formula Weight: 409.90856
MOL File: 455311-98-5.mol

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1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Property

storage temp.: 2-8°C
solubility: DMSO: >10mg/mL
form: powder
color: white to off-white

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Safety

WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B2938
Product name: BEPP monohydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $174
Updated: 2024/03/01

Sigma-Aldrich

Product number: B2938
Product name: BEPP monohydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $564
Updated: 2024/03/01

TRC

Product number: B130003
Product name: BEPP monohydrochloride
Packaging: 50mg
Price: $940
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008347
Product name: BEPP MONOHYDROCHLORIDE
Purity: 95.00%
Packaging: 25MG
Price: $1046.61
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008347
Product name: BEPP MONOHYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $701.95
Updated: 2021/12/16

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1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Chemical Properties,Usage,Production

Uses

BEPP Monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator. Apoptosis.

Biological Activity

BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinase, inducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities), modulating activities of eIF2α, NF-KB, ATF-3, and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR.

1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Suppliers

Canada 1 CHINA 4 Finland 1 United States 3 Global 9

Toronto Research Chemicals

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455311-98-5, 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochlorideRelated Search:

1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride

BEPP monohydrochloride

455311-98-5