ChemicalBook > CAS DataBase List > 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
- Product Name
- 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
- CAS No.
- 455311-98-5
- Chemical Name
- 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
- Synonyms
- BEPP monohydrochloride;1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
- CBNumber
- CB02755821
- Molecular Formula
- C23H24ClN3O2
- Formula Weight
- 409.90856
- MOL File
- 455311-98-5.mol
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1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Property
- storage temp.
- 2-8°C
- solubility
- DMSO: >10mg/mL
- form
- powder
- color
- white to off-white
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Safety
- WGK Germany
- 1
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- B2938
- Product name
- BEPP monohydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $174
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- B2938
- Product name
- BEPP monohydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $564
- Updated
- 2024/03/01
TRC
- Product number
- B130003
- Product name
- BEPP monohydrochloride
- Packaging
- 50mg
- Price
- $940
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0008347
- Product name
- BEPP MONOHYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $1046.61
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0008347
- Product name
- BEPP MONOHYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $701.95
- Updated
- 2021/12/16
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1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Chemical Properties,Usage,Production
Uses
BEPP Monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator. Apoptosis.
Biological Activity
BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinase, inducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities), modulating activities of eIF2α, NF-KB, ATF-3, and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR.
1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride Suppliers
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