HUMAN HGF
Description Source Background- Product Name
- HUMAN HGF
- CAS No.
- 953836-17-4
- Chemical Name
- HUMAN HGF
- Synonyms
- HGF;HPTA;HGFB;RHHGF;F-TCF;HUMAN SF;HUMAN HGF;HGF, HUMAN;HUMAN HPTA;REC SF (HUMAN)
- CBNumber
- CB0283412
- Formula Weight
- 0
- MOL File
- Mol file
HUMAN HGF Property
- storage temp.
- −20°C
- form
- powder
- biological source
- human
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/38
- Safety Statements
- 22-24/25-26
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- H9661
- Product name
- Hepatocyte Growth Factor human
- Purity
- HGF, recombinant, expressed in NSO cells, suitable for cell culture
- Packaging
- 5μG
- Price
- $338
- Updated
- 2025/07/31
- Product number
- SRP6014
- Product name
- HGF human
- Purity
- recombinant, expressed in CHO cells, ≥97% (SDS-PAGE), ≥97% (HPLC)
- Packaging
- 10 μg
- Price
- $481
- Updated
- 2025/07/31
- Product number
- H9661
- Product name
- Hepatocyte Growth Factor human
- Purity
- HGF, recombinant, expressed in NSO cells, suitable for cell culture
- Packaging
- 25μG
- Price
- $675
- Updated
- 2025/07/31
- Product number
- H5791
- Product name
- Hepatocyte Growth Factor human
- Purity
- HGF, recombinant, expressed in HEK 293 cells, HumanKine<SUP>®</SUP>, suitable for cell culture
- Packaging
- 10 μg
- Price
- $338
- Updated
- 2025/07/31
- Product number
- H5791
- Product name
- Hepatocyte Growth Factor human
- Purity
- HGF, recombinant, expressed in HEK 293 cells, HumanKine<SUP>®</SUP>, suitable for cell culture
- Packaging
- 5 x 10 μg
- Price
- $844
- Updated
- 2025/07/31
HUMAN HGF Chemical Properties,Usage,Production
Uses
Hepatocyte Growth Factor human has been used as a growth factor cocktail to suspend rat fibrogen/thrombin cells. It has also been used to study the tyrosine phosphorylation of MET (MET proto-oncogene, receptor tyrosine kinase) in myxofibrosarcoma cell line.
General Description
The HGF gene spans ～70 kb and consists of 18 exons interrupted by 17 introns. The organization of the human HGF gene is highly homologous to that of human plasminogen. HGF maps to the long arm of human chromosome 7, 7q21.1.
Biochem/physiol Actions
HGF is a multifunctional cytokine that promotes mitogenesis, migration, invasion, and morphogenesis. It is a potent mitogen, stimulating the growth of hepatocytes, renal tubular epithelial cells, epidermal keratinocytes, epidermal melanocytes, Mv1Lu (mink lung epithelial cells), and BALB/MK (mouse keratinocytes). HGF inhibits the growth of B6/F1 (mouse melanoma) cells, KB (human squamous carcinoma) cells, and HepG2 (human hepatoma) cells. HGF is the ligand for the tyrosine kinase receptor encoded by the met proto-oncogene.
Description
Hepatocyte Growth Factor Human Recombinant produced in Baculovirus is a heterodimer, non-glycosylated, polypeptide chain containing 697 a.a and having a total molecular mass of 78.0 KDa.
The HGF is purified by proprietary chromatographic techniques.
Source
Insect cells
Background
Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis.
HUMAN HGF Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN HGF Suppliers
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