ChemicalBook > CAS DataBase List > TC-MCH 7c

TC-MCH 7c

Product Name
TC-MCH 7c
CAS No.
864756-35-4
Chemical Name
TC-MCH 7c
Synonyms
TC-MCH 7c;TCMCH 7c,TC MCH 7c;TC-MCH 7c, 10 mM in DMSO;4-(4-Fluoro-benzyloxy)-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1H-pyridin-2-one;4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone;2(1H)-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
CBNumber
CB03037553
Molecular Formula
C24H25FN2O3
Formula Weight
408.47
MOL File
864756-35-4.mol
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TC-MCH 7c Property

Melting point:
124-126 °C
Boiling point:
606.3±55.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 100 mM in 1eq. HCl and to 50 mM in DMSO
form 
Powder
pka
9.60±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4365
Product name
TC-MCH7c
Purity
≥97%(HPLC)
Packaging
10
Price
$293
Updated
2021/12/16
TRC
Product number
T127685
Product name
TC-MCH7c
Packaging
10mg
Price
$270
Updated
2021/12/16
Usbiological
Product number
256850
Product name
TC-MCH 7c
Packaging
10mg
Price
$602
Updated
2021/12/16
ChemScene
Product number
CS-0028998
Product name
TC-MCH7c
Purity
>99.0%
Packaging
1mg
Price
$195
Updated
2021/12/16
ApexBio Technology
Product number
B5564
Product name
TC-MCH7c
Packaging
10mg
Price
$434
Updated
2021/12/16
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TC-MCH 7c Chemical Properties,Usage,Production

Uses

TC-MCH 7c is a potent melanin-concentrating hormone 1 receptor antagonist.

in vivo

TC-MCH 7c (oral; 3-30 mg/kg; once-daily for 1.5 months) exhibits excellent body weight reduction in a dose-dependent manner in DIO mice model[1].
TC-MCH 7c (oral; 3-30 mg/kg) with 30 mg/kg has plasma concentrations of 5.1, 1.8, and 0.7 μM at 2, 15, and 24 hours, respectively[2].

Animal Model:C57BL/6J DIO mice[1]
Dosage:3, 10 and 30 mg/kg
Administration:Oral; once-daily for 1.5 months
Result:Exhibited excellent body weight reduction in a dose-dependent manner.
Animal Model:Diet-induced obesity mice[2]
Dosage:3, 10 and 30 mg/kg (Pharmacokinetic Analysis)
Administration:Oral
Result:Plasma concentrations at 2, 15, and 24 hours were 5.1, 1.8, and 0.7 μM, respectively.

storage

Store at RT

TC-MCH 7c Preparation Products And Raw materials

Raw materials

Preparation Products

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TC-MCH 7c Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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China
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15911056312
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010-60605840 15801484223;
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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400-6206333 13167063860
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Chongqing Boer Biotechnology Co., Ltd.
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Absin Bioscience Inc.
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Qingdao Jieshikang Biotechnology Co., Ltd.
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864756-35-4, TC-MCH 7cRelated Search:


  • TC-MCH 7c
  • 4-(4-Fluoro-benzyloxy)-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1H-pyridin-2-one
  • 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone
  • TCMCH 7c,TC MCH 7c
  • 2(1H)-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
  • TC-MCH 7c, 10 mM in DMSO
  • 864756-35-4
  • C24H25FN2O3