ChemicalBook > CAS DataBase List > TC-MCH 7c
TC-MCH 7c
- Product Name
- TC-MCH 7c
- CAS No.
- 864756-35-4
- Chemical Name
- TC-MCH 7c
- Synonyms
- TC-MCH 7c;TCMCH 7c,TC MCH 7c;TC-MCH 7c, 10 mM in DMSO;4-(4-Fluoro-benzyloxy)-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1H-pyridin-2-one;4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone;2(1H)-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
- CBNumber
- CB03037553
- Molecular Formula
- C24H25FN2O3
- Formula Weight
- 408.47
- MOL File
- 864756-35-4.mol
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TC-MCH 7c Property
- Melting point:
- 124-126 °C
- Boiling point:
- 606.3±55.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- Soluble to 100 mM in 1eq. HCl and to 50 mM in DMSO
- form
- Powder
- pka
- 9.60±0.20(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Tocris
- Product number
- 4365
- Product name
- TC-MCH7c
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $293
- Updated
- 2021/12/16
TRC
- Product number
- T127685
- Product name
- TC-MCH7c
- Packaging
- 10mg
- Price
- $270
- Updated
- 2021/12/16
Usbiological
- Product number
- 256850
- Product name
- TC-MCH 7c
- Packaging
- 10mg
- Price
- $602
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0028998
- Product name
- TC-MCH7c
- Purity
- >99.0%
- Packaging
- 1mg
- Price
- $195
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B5564
- Product name
- TC-MCH7c
- Packaging
- 10mg
- Price
- $434
- Updated
- 2021/12/16
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TC-MCH 7c Chemical Properties,Usage,Production
Uses
TC-MCH 7c is a potent melanin-concentrating hormone 1 receptor antagonist.
in vivo
TC-MCH 7c (oral; 3-30 mg/kg; once-daily for 1.5 months) exhibits excellent body weight reduction in a dose-dependent manner in DIO mice model[1].
TC-MCH 7c (oral; 3-30 mg/kg) with 30 mg/kg has plasma concentrations of 5.1, 1.8, and 0.7 μM at 2, 15, and 24 hours, respectively[2].
| Animal Model: | C57BL/6J DIO mice[1] |
| Dosage: | 3, 10 and 30 mg/kg |
| Administration: | Oral; once-daily for 1.5 months |
| Result: | Exhibited excellent body weight reduction in a dose-dependent manner. |
| Animal Model: | Diet-induced obesity mice[2] |
| Dosage: | 3, 10 and 30 mg/kg (Pharmacokinetic Analysis) |
| Administration: | Oral |
| Result: | Plasma concentrations at 2, 15, and 24 hours were 5.1, 1.8, and 0.7 μM, respectively. |
storage
Store at RT
TC-MCH 7c Preparation Products And Raw materials
Raw materials
Preparation Products
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