ChemicalBook > CAS DataBase List > (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
- Product Name
- (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
- CAS No.
- 160800-65-7
- Chemical Name
- (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
- Synonyms
- Boc-Dap-NE;N-Boc-Dap-NE;Antibody-drug conjugates linkers,inhibit,ADC Linkers,BOC Dap NE,Inhibitor,BOCDapNE;(2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-N-[(1S,2R)-1-hydroxy-1-phenyl-2-propyl]-3-methoxy-2-methylpropanamide;tert-butyl (S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate;(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-
- CBNumber
- CB03053768
- Molecular Formula
- C23H36N2O5
- Formula Weight
- 420.54
- MOL File
- 160800-65-7.mol
More
Less
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Property
- Melting point:
- 55-57 °C
- Boiling point:
- 589.1±50.0 °C(Predicted)
- Density
- 1.125±0.06 g/cm3(Predicted)
- solubility
- DMSO: 100 mg/mL (237.79 mM)
- pka
- 13.66±0.20(Predicted)
- Water Solubility
- Water: < 0.1 mg/mL (insoluble)
- InChIKey
- XJDVGABQIFOWFC-SCQOQHIRSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC[C@H]1[C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)=O
More
Less
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-M2968
- Product name
- Boc-Dap-NE
- Packaging
- 1g
- Price
- $1400
- Updated
- 2021/12/16
Ambeed
- Product number
- A104664
- Product name
- (S)-tert-Butyl2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $152
- Updated
- 2021/12/16
Ambeed
- Product number
- A104664
- Product name
- (S)-tert-Butyl2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
- Purity
- 98+%
- Packaging
- 250mg
- Price
- $284
- Updated
- 2021/12/16
Ambeed
- Product number
- A104664
- Product name
- (S)-tert-Butyl2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
- Purity
- 98+%
- Packaging
- 1g
- Price
- $710
- Updated
- 2021/12/16
More
Less
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Chemical Properties,Usage,Production
Uses
Boc-Dap-NE, a dipeptide, is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
Biological Activity
Boc-Dap-NE is a dipeptide used as a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
target
Cleavable
|
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Suppliers
- Tel
- 13666392288
- jhyylcj@163.com
- Country
- China
- ProdList
- 64
- Advantage
- 58
- Tel
- 021-58950125
- Fax
- 021-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 706
- Advantage
- 58
- Tel
- 18106521904
- Fax
- 0571-88678987
- 3095213753@qq.com
- Country
- China
- ProdList
- 16
- Advantage
- 58
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9452
- Advantage
- 58
- Tel
- 022-66211079 13212288319
- Fax
- qq1405432731
- sales@chempharmatech.com
- Country
- China
- ProdList
- 816
- Advantage
- 55
- Tel
- 028-84502008 13568869383
- Fax
- 028-66476329
- sales@hygeiapharm.com
- Country
- China
- ProdList
- 295
- Advantage
- 55
- Tel
- 021-52996696,15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4182
- Advantage
- 55
- Tel
- 021-50426030 13856289449
- Fax
- 021-50426030
- 2630597085@qq.com
- Country
- China
- ProdList
- 1889
- Advantage
- 55
- Tel
- 18086626237 18086626237
- Fax
- qq:2693528373
- sales@debyesci.com
- Country
- China
- ProdList
- 2643
- Advantage
- 56
- Tel
- 021-58088081 Q2816483246
- Fax
- QQ3382968513
- danping@shsendpharm.com
- Country
- China
- ProdList
- 3139
- Advantage
- 55
- Tel
- 13812573443
- Fax
- -
- tongbenwan22@163.com
- Country
- China
- ProdList
- 1998
- Advantage
- 55
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9604
- Advantage
- 55
- Tel
- QQ:65489617 15618227136
- Fax
- 21-5161 9052
- info@SuperLan-chem.com
- Country
- China
- ProdList
- 9779
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12308
- Advantage
- 58
- Tel
- +86-530-529 6766,+86-15666160102 15666160102
- Fax
- 0530-529 6766
- info@chuangli-chem.com
- Country
- China
- ProdList
- 876
- Advantage
- 55
- Tel
- 025-58851090 13611564524
- Fax
- (6)02557626880
- lwan@aikonchem.com
- Country
- China
- ProdList
- 15952
- Advantage
- 58
- Tel
- 021-61469567 18521078705
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- 021-58958002 18930822973
- Fax
- 021-58958618
- xiaoyangw@gmail.com
- Country
- China
- ProdList
- 2129
- Advantage
- 58
- Tel
- 025-84767922 18936879710
- sales@abydoscientific.com
- Country
- China
- ProdList
- 1011
- Advantage
- 58
- Tel
- 19981275275
- sales@zsdbiopharm.com
- Country
- China
- ProdList
- 281
- Advantage
- 58
- Tel
- 021-50676523 18019098996
- info@acelybio.com
- Country
- China
- ProdList
- 3967
- Advantage
- 58
- Tel
- +8618530059196
- sale04@alfachem.cn
- Country
- China
- ProdList
- 12803
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19915
- Advantage
- 58
- Tel
- 571-86758373 +8613588754946
- Fax
- 0086-571-81131109
- sales@huarongpharm.com
- Country
- CHINA
- ProdList
- 3149
- Advantage
- 58
- Tel
- 0371-63284658 18135795563
- Fax
- QQ:2885349392
- 2885349392@qq.com
- Country
- China
- ProdList
- 9997
- Advantage
- 58
- Tel
- 021 60642329 19946252459
- Fax
- QQ:1072302796
- sales@galedo-bio.com
- Country
- China
- ProdList
- 2018
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9414
- Advantage
- 58
- Tel
- 0519-85788828 13775037613
- sales@chemrenpharm.com
- Country
- China
- ProdList
- 3574
- Advantage
- 58
- Tel
- 63313187 15358055255
- Fax
- QQ:63313187
- 63313187@qq.com
- Country
- China
- ProdList
- 1971
- Advantage
- 58
- Tel
- 13173652190
- pomy@tanzhenbio.com
- Country
- China
- ProdList
- 1618
- Advantage
- 58
- Tel
- 15869524721
- 3525679403@qq.com
- Country
- China
- ProdList
- 3688
- Advantage
- 58
- Tel
- 0571-89903882 13626641628
- jiangnan@huidabiotech.com
- Country
- China
- ProdList
- 3659
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44486
- Advantage
- 58
- Tel
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29778
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 39997
- Advantage
- 58
- Tel
- 15221533763
- suzhourich@163.com
- Country
- China
- ProdList
- 992
- Advantage
- 58
- Tel
- 15051477682
- changming.pan@csynbio.com
- Country
- China
- ProdList
- 225
- Advantage
- 58
- Tel
- 400-1647117 15221909166
- product02@bidepharm.com
- Country
- China
- ProdList
- 63720
- Advantage
- 58
- Tel
- 13549236410
- sales@invivochem.cn
- Country
- China
- ProdList
- 6749
- Advantage
- 58
- Tel
- 15851462628 15851462628
- 2680463261@qq.com
- Country
- China
- ProdList
- 5010
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24018
- Advantage
- 58
- Tel
- 027-59105166 13125137732
- 2853863890@qq.com
- Country
- China
- ProdList
- 2932
- Advantage
- 58
- Tel
- 021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29803
- Advantage
- 58
- Tel
- +86-021-50266790 Q2816483246
- Fax
- 021-50266790
- sale@shsendpharm.com
- Country
- China
- ProdList
- 272
- Advantage
- 50
- Tel
- 13720134139 13720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 5278
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50751
- Advantage
- 58
- Tel
- 15360509991
- 605501357@qq.com
- Country
- China
- ProdList
- 9
- Advantage
- 58
- Tel
- 14760821013 14760821013
- 1816280386@qq.com
- Country
- China
- ProdList
- 6148
- Advantage
- 58
- Tel
- 18912729622
- 66161984@qq.com
- Country
- China
- ProdList
- 757
- Advantage
- 58
- Tel
- 021-54306202 18917919676
- info@hanhongsci.com
- Country
- China
- ProdList
- 29989
- Advantage
- 58