(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate

Product Name: (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
CAS No.: 160800-65-7
Chemical Name: (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
Synonyms: Boc-Dap-NE;N-Boc-Dap-NE;Antibody-drug conjugates linkers,inhibit,ADC Linkers,BOC Dap NE,Inhibitor,BOCDapNE;(2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-N-[(1S,2R)-1-hydroxy-1-phenyl-2-propyl]-3-methoxy-2-methylpropanamide;tert-butyl (2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidine-1-carboxylate;tert-butyl (S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate;(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-
CBNumber: CB03053768
Molecular Formula: C23H36N2O5
Formula Weight: 420.54
MOL File: 160800-65-7.mol

More

Less

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Property

Melting point:: 55-57 °C
Boiling point:: 589.1±50.0 °C(Predicted)
Density: 1.125±0.06 g/cm3(Predicted)
solubility: DMSO: 100 mg/mL (237.79 mM)
pka: 13.66±0.20(Predicted)
form: Solid
color: White to off-white
Water Solubility: Water: < 0.1 mg/mL (insoluble)
InChIKey: XJDVGABQIFOWFC-SCQOQHIRSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC[C@H]1[C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)=O

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-M2968
Product name: Boc-Dap-NE
Packaging: 1g
Price: $1400
Updated: 2021/12/16

Ambeed

Product number: A104664
Product name: (S)-tert-Butyl2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
Purity: 98+%
Packaging: 100mg
Price: $152
Updated: 2021/12/16

Ambeed

Product number: A104664
Product name: (S)-tert-Butyl2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
Purity: 98+%
Packaging: 250mg
Price: $284
Updated: 2021/12/16

Ambeed

Product number: A104664
Product name: (S)-tert-Butyl2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
Purity: 98+%
Packaging: 1g
Price: $710
Updated: 2021/12/16

More

Less

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Chemical Properties,Usage,Production

Uses

Boc-Dap-NE, a dipeptide, is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

Biological Activity

Boc-Dap-NE is a dipeptide used as a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

target

Cleavable

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Suppliers

China 65 United States 6 Global 71

SuZhou JianHua Pharmaceutical Co. Ltd

Tel: 13666392288
Email: jhyylcj@163.com
Country: China
ProdList: 64
Advantage: 58

Hangzhou qinyu Pharmaceutical Technology Co. , Ltd.

Tel: 18106521904
Fax: 0571-88678987
Email: 3095213753@qq.com
Country: China
ProdList: 14
Advantage: 58

YJ Pharma

Tel: 13962794339 13962794339
Email: 3686954964@qq.com
Country: China
ProdList: 168
Advantage: 58

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 872
Advantage: 55

Huadong Microbiology Co., Ltd.

Tel: 15858880160
Email: dingya@eastchinapharm.com
Country: China
ProdList: 54
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9458
Advantage: 58

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 299
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4566
Advantage: 55

Tongling HengYou Biotechnology Co., Ltd.

Tel: 021-50426030 13856289449
Fax: 021-50426030
Email: 2630597085@qq.com
Country: China
ProdList: 1889
Advantage: 55

DebyeTec.com Inc.

Tel: 18086626237 18086626237
Fax: qq:2693528373
Email: sales@debyesci.com
Country: China
ProdList: 2645
Advantage: 56

160800-65-7, (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylateRelated Search:

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-

Boc-Dap-NE

N-Boc-Dap-NE

Antibody-drug conjugates linkers,inhibit,ADC Linkers,BOC Dap NE,Inhibitor,BOCDapNE

(2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-N-[(1S,2R)-1-hydroxy-1-phenyl-2-propyl]-3-methoxy-2-methylpropanamide

tert-butyl (S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate

tert-butyl (2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidine-1-carboxylate

160800-65-7

ADC LINKER

ADCs Linkers

ADCs