GSK-F1

Product Name: GSK-F1
CAS No.: 1402345-92-9
Chemical Name: GSK-F1
Synonyms: GSK-F1;CS-2666;rac-GSK-F1;PI4KA inhibitor-F1;GSK-F1, 10 mM in DMSO;5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide;5-{2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]-3,4-dihydro-6-quinazolinyl}-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide;3-Pyridinesulfonamide, 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-;hepatitis C virus,Phosphoinositide 3-kinase,Inhibitor,HEK293-AT1 cells,GSK-F-1,PI4K,Phosphatidylinositol 4 kinases,GSK-F1,HCV,GSKF1,COS-7,inhibit,GSK F1,PI4 kinases,PI3K
CBNumber: CB03067552
Molecular Formula: C27H18F5N5O4S
Formula Weight: 603.52
MOL File: 1402345-92-9.mol

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GSK-F1 Property

Boiling point:: 744.3±70.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C, sealed storage, away from moisture and light
solubility: DMSO : 125 mg/mL (207.12 mM; Need ultrasonic)
form: Solid
pka: 5.66±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Adipogen Life Sciences

Product number: SYN-1220-M005
Product name: GSK-F1
Purity: ≥95%
Packaging: 5mg
Price: $270
Updated: 2021/12/16

Adipogen Life Sciences

Product number: SYN-1220-M010
Product name: GSK-F1
Purity: ≥95%
Packaging: 10mg
Price: $421
Updated: 2021/12/16

DC Chemicals

Product number: DC10064
Product name: GSK-F1
Purity: >98%
Packaging: 10mg
Price: $300
Updated: 2021/12/16

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GSK-F1 Chemical Properties,Usage,Production

Uses

GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research[1].

IC 50

PI4KA: 8.0 (pIC₅₀); PI3KD: 6.4 (pIC₅₀); PI4KB: 5.9 (pIC₅₀); PI3KB: 5.9 (pIC₅₀); PI3KG: 5.9 (pIC₅₀); PI3KA: 5.8 (pIC₅₀)

References

[1] Bojjireddy N, et al. Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. J Biol Chem. 2014 Feb 28;289(9):6120-32. DOI:10.1074/jbc.M113.531426

GSK-F1 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK-F1 Suppliers

China 32 United Kingdom 1 United States 3 Global 36

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070 13913916777
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16055
Advantage: 64

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 7999
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9532
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

1402345-92-9, GSK-F1Related Search:

GSK-F1

rac-GSK-F1

CS-2666

PI4KA inhibitor-F1

3-Pyridinesulfonamide, 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-

5-{2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]-3,4-dihydro-6-quinazolinyl}-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide

hepatitis C virus,Phosphoinositide 3-kinase,Inhibitor,HEK293-AT1 cells,GSK-F-1,PI4K,Phosphatidylinositol 4 kinases,GSK-F1,HCV,GSKF1,COS-7,inhibit,GSK F1,PI4 kinases,PI3K

GSK-F1, 10 mM in DMSO

5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide

1402345-92-9

C27H18F5N5O4S