GSK-F1

Product Name: GSK-F1
CAS No.: 1402345-92-9
Chemical Name: GSK-F1
Synonyms: GSK-F1;CS-2666;rac-GSK-F1;PI4KA inhibitor-F1;GSK-F1, 10 mM in DMSO;5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide;5-{2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]-3,4-dihydro-6-quinazolinyl}-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide;3-Pyridinesulfonamide, 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-;hepatitis C virus,Phosphoinositide 3-kinase,Inhibitor,HEK293-AT1 cells,GSK-F-1,PI4K,Phosphatidylinositol 4 kinases,GSK-F1,HCV,GSKF1,COS-7,inhibit,GSK F1,PI4 kinases,PI3K
CBNumber: CB03067552
Molecular Formula: C27H18F5N5O4S
Formula Weight: 603.52
MOL File: 1402345-92-9.mol

More

Less

GSK-F1 Property

Boiling point:: 744.3±70.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C, sealed storage, away from moisture and light
solubility: DMSO : 125 mg/mL (207.12 mM; Need ultrasonic)
form: Solid
pka: 5.66±0.50(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Adipogen Life Sciences

Product number: SYN-1220-M005
Product name: GSK-F1
Purity: ≥95%
Packaging: 5mg
Price: $270
Updated: 2021/12/16

Adipogen Life Sciences

Product number: SYN-1220-M010
Product name: GSK-F1
Purity: ≥95%
Packaging: 10mg
Price: $421
Updated: 2021/12/16

DC Chemicals

Product number: DC10064
Product name: GSK-F1
Purity: >98%
Packaging: 10mg
Price: $300
Updated: 2021/12/16

More

Less

GSK-F1 Chemical Properties,Usage,Production

Uses

GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research[1].

IC 50

PI4KA: 8.0 (pIC₅₀); PI3KD: 6.4 (pIC₅₀); PI4KB: 5.9 (pIC₅₀); PI3KB: 5.9 (pIC₅₀); PI3KG: 5.9 (pIC₅₀); PI3KA: 5.8 (pIC₅₀)

References

[1] Bojjireddy N, et al. Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. J Biol Chem. 2014 Feb 28;289(9):6120-32. DOI:10.1074/jbc.M113.531426

GSK-F1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GSK-F1 Suppliers

China 30 United Kingdom 1 United States 3 Global 34

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9119
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

1402345-92-9, GSK-F1Related Search:

GSK-F1

rac-GSK-F1

CS-2666

PI4KA inhibitor-F1

3-Pyridinesulfonamide, 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-

5-{2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]-3,4-dihydro-6-quinazolinyl}-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide

hepatitis C virus,Phosphoinositide 3-kinase,Inhibitor,HEK293-AT1 cells,GSK-F-1,PI4K,Phosphatidylinositol 4 kinases,GSK-F1,HCV,GSKF1,COS-7,inhibit,GSK F1,PI4 kinases,PI3K

GSK-F1, 10 mM in DMSO

5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide

1402345-92-9

C27H18F5N5O4S