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glucagon receptor antagonists-4

Product Name
glucagon receptor antagonists-4
CAS No.
1393124-08-7
Chemical Name
glucagon receptor antagonists-4
Synonyms
CS-2641;PF6291874;GCGR-IN-17;PF-06291874 >=98% (HPLC);Glucagon Receptor Antagonist 4;lucagon receptor antagonists-4;glucagon receptor antagonists-4;PF06291874;PF-06291874;PF 06291874;PF-06291874(glucagon receptor antagonists-4);N-{4-[(1S)-1-{3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]benzoyl}-β-alanine
CBNumber
CB03133347
Molecular Formula
C26H28F3N3O4
Formula Weight
503.51
MOL File
1393124-08-7.mol
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glucagon receptor antagonists-4 Property

Boiling point:
675.0±55.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 50mg/mL; DMSO: 50mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL; Ethanol: 0.5mg/mL
form 
A crystalline solid
pka
4.28±0.10(Predicted)
color 
White to off-white
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22164
Product name
Glucagon Receptor Antagonist 4
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
22164
Product name
Glucagon Receptor Antagonist 4
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
22164
Product name
Glucagon Receptor Antagonist 4
Packaging
10mg
Price
$169
Updated
2024/03/01
Cayman Chemical
Product number
22164
Product name
Glucagon Receptor Antagonist 4
Packaging
25mg
Price
$381
Updated
2024/03/01
TRC
Product number
P294103
Product name
PF-06291874
Packaging
10mg
Price
$315
Updated
2021/12/16
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glucagon receptor antagonists-4 Chemical Properties,Usage,Production

Uses

PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.

glucagon receptor antagonists-4 Preparation Products And Raw materials

Raw materials

Preparation Products

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1393124-08-7, glucagon receptor antagonists-4Related Search:


  • glucagon receptor antagonists-4
  • N-{4-[(1S)-1-{3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]benzoyl}-β-alanine
  • lucagon receptor antagonists-4
  • Glucagon Receptor Antagonist 4
  • GCGR-IN-17
  • PF06291874;PF-06291874;PF 06291874
  • PF6291874
  • CS-2641
  • PF-06291874(glucagon receptor antagonists-4)
  • β-Alanine, N-[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]-
  • PF-06291874 >=98% (HPLC)
  • inhibit,Inhibitor,glucagon,bioavailability,Glucagon Receptor,PF 06291874,Glucagon receptor antagonists4,clearance,GCGR,PF-06291874,oral,PF06291874,Glucagon receptor antagonists 4
  • 3-({4-[(1S)-1-{3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]phenyl}formamido)propanoic acid
  • 1393124-08-7
  • API