ChemicalBook > CAS DataBase List > 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Product Name
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
CAS No.
740081-22-5
Chemical Name
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
Synonyms
6-acetoxy-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline;4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl ...;4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate;6-Quinazolinol, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate
CBNumber
CB03145935
Molecular Formula
C17H13ClFN3O3
Formula Weight
361.75
MOL File
740081-22-5.mol
More
Less

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Property

Boiling point:
454.4±45.0 °C(Predicted)
Density 
1.425±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
5.22±0.30(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C989238
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylAcetate
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
5764DN
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Packaging
1g
Price
$92
Updated
2021/12/16
Chemenu
Product number
CM216563
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Purity
97%
Packaging
5g
Price
$184
Updated
2021/12/16
Alichem
Product number
740081225
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Packaging
5g
Price
$189
Updated
2021/12/16
Ambeed
Product number
A143974
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Purity
97%
Packaging
25g
Price
$223
Updated
2021/12/16
More
Less

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Chemical Properties,Usage,Production

Description

AZD3759 is a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) on the basis of gefitinib and has been proven to enter the central nervous system. Although the promising antitumor effects of AZD3759 on non-small cell lung cancer (NSCLC) have been demonstrated in clinical trials, the regulatory effects of this inhibitor on the antitumor efficacy of radiation (RA) are unclear. AZD3759 Intermediate 2 is a key intermediate in the synthesis of AZD3759.

Uses

AZD3759 Intermediate 2 can be used as a pharmaceutical intermediate.

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Suppliers

Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
ATK CHEMICAL COMPANY LIMITED
Tel
3429815786 13301662590
Fax
+86-21-51619052
Email
sales@atkchemical.com
Country
China
ProdList
10060
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Shanghai XingTai Pharmaceutical Technology co., LTD
Tel
15801747407
Fax
+86 021 51388225
Email
sales01@suntechpharma.com
Country
China
ProdList
123
Advantage
58
Kaixin Chemical (Hong Kong) Limited
Tel
010-88886666-01 13112345678
Fax
CDXH21@126.com
Email
loyson@tcypharm.com
Country
China
ProdList
595
Advantage
55
Dezhou LonWel Pharmaceutical Technology Co., Ltd.
Tel
13761310616
Fax
QQ: 39324283
Email
39324283@qq.com
Country
China
ProdList
1985
Advantage
58
Shijiazhuang Als Pharmaceutical Technology Co., Ltd.
Tel
0311-85150550 18932901920
Fax
0311-85150550
Email
alspharm@163.com
Country
China
ProdList
231
Advantage
58
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15952
Advantage
58
Shanghai He Huan Chemical Co., Ltd.
Tel
021-60345187 13917602471
Fax
021-60345187
Email
lzz841106@aliyun.com
Country
China
ProdList
9907
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-0371-55051623 18137891487
Fax
QQ:2853979817
Email
2853979817@qq.com
Country
China
ProdList
9828
Advantage
58
More
Less

View Lastest Price from 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate manufacturers

Shanghai Rlavie Technology Co ltd
Product
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate 740081-22-5
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
25kgs/month
Release date
2021-11-18
Career Henan Chemical Co
Product
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate 740081-22-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-17

740081-22-5, 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetateRelated Search:


  • 6-acetoxy-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline
  • 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
  • 6-Quinazolinol, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate
  • 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl ...
  • 740081-22-5