ChemicalBook > CAS DataBase List > Lp-PLA2 -IN-1

Lp-PLA2 -IN-1

Product Name
Lp-PLA2 -IN-1
CAS No.
1420367-28-7
Chemical Name
Lp-PLA2 -IN-1
Synonyms
Lp-PLA2 -IN-1;Lp-PLA2 inhibitor;Lp-PLA2 inhibitor 1;GSK 2814338;GSK-2814338;Lp-PLA2 -IN-1(GSK2814338);inhibit,Lp-PLA-2-IN-1,LpPLA2IN1,Inhibitor,Lp PLA2 IN 1,Phospholipase;8-((3,5-Difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-1,2,3,4-tetrahydro-6H-pyrimido[1,6-a]pyrimidin-6-one;6H-Pyrimido[1,6-a]pyrimidin-6-one, 8-[[3,5-difluoro-4-[[6-(trifluoromethyl)-3-pyridinyl]oxy]phenyl]methoxy]-1,2,3,4-tetrahydro-1-methyl-
CBNumber
CB03152083
Molecular Formula
C21H17F5N4O3
Formula Weight
468.38
MOL File
1420367-28-7.mol
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Lp-PLA2 -IN-1 Property

Boiling point:
483.5±55.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Ethanol:25.0(Max Conc. mg/mL);53.38(Max Conc. mM)
pka
3.84±0.40(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5918
Product name
Lp-PLA2-IN-1
Purity
99.46%
Packaging
1mg
Price
$168
Updated
2021/12/16
ChemScene
Product number
CS-5918
Product name
Lp-PLA2-IN-1
Purity
99.46%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-5918
Product name
Lp-PLA2-IN-1
Purity
99.46%
Packaging
10mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-5918
Product name
Lp-PLA2-IN-1
Purity
99.46%
Packaging
50mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-5918
Product name
Lp-PLA2-IN-1
Purity
99.46%
Packaging
100mg
Price
$2520
Updated
2021/12/16
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Lp-PLA2 -IN-1 Chemical Properties,Usage,Production

Uses

Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer's disease research[1].

IC 50

Lp-PLA2

References

[1] Zehong Wan, et al. Bicyclic pyrimidone compounds. WO2013014185A1.

Lp-PLA2 -IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Lp-PLA2 -IN-1 Suppliers

MedChemexpress LLC
Tel
021-58955995
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609-228-5909
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sales@medchemexpress.cn
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United States
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Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
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3003855609@qq.com
Country
China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
Country
China
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Qingdao IniKem BioPharmaTech Co.,Ltd
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0532-58268781 18561687109
Fax
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sales@inikem.com
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China
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
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Musechem
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United States
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Twochem Co.Ltd.
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QQ 3285589261
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Beijing Minruida Technology Co., Ltd.
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010-82387566 18001021521;
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82387566-801
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China
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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
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18081075745
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chemflowtech@sina.com
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China
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TargetMol Chemicals Inc.
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marketing@targetmol.com
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United States
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1420367-28-7, Lp-PLA2 -IN-1Related Search:


  • Lp-PLA2 inhibitor
  • GSK 2814338;GSK-2814338
  • Lp-PLA2 -IN-1
  • Lp-PLA2 inhibitor 1
  • Lp-PLA2 -IN-1(GSK2814338)
  • inhibit,Lp-PLA-2-IN-1,LpPLA2IN1,Inhibitor,Lp PLA2 IN 1,Phospholipase
  • 6H-Pyrimido[1,6-a]pyrimidin-6-one, 8-[[3,5-difluoro-4-[[6-(trifluoromethyl)-3-pyridinyl]oxy]phenyl]methoxy]-1,2,3,4-tetrahydro-1-methyl-
  • 8-((3,5-Difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-1,2,3,4-tetrahydro-6H-pyrimido[1,6-a]pyrimidin-6-one
  • 1420367-28-7