Se-Aspirin
- Product Name
- Se-Aspirin
- CAS No.
- 1850293-95-6
- Chemical Name
- Se-Aspirin
- Synonyms
- Se-Aspirin;2-((2-Selenocyanatoethyl)carbamoyl)phenyl acetate;Selenocyanic acid, 2-[[2-(acetyloxy)benzoyl]amino]ethyl ester
- CBNumber
- CB03152740
- Molecular Formula
- C12H12N2O3Se
- Formula Weight
- 311.2
- MOL File
- 1850293-95-6.mol
Se-Aspirin Property
- storage temp.
- Store at -20°C
- solubility
- ≤10mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
- form
- crystalline solid
- pka
- 13.48±0.46(Predicted)
N-Bromosuccinimide Price
- Product number
- 19315
- Product name
- Se-Aspirin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 19315
- Product name
- Se-Aspirin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
- Product number
- 19315
- Product name
- Se-Aspirin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $243
- Updated
- 2024/03/01
- Product number
- 19315
- Product name
- Se-Aspirin
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $987
- Updated
- 2024/03/01
- Product number
- C5667
- Product name
- Se-Aspirin
- Packaging
- 10mg
- Price
- $277
- Updated
- 2021/12/16
Se-Aspirin Chemical Properties,Usage,Production
Description
Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 μM). It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage. Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.
Uses
Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 μM). It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage. Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.[Cayman Chemical]
References
[1] plano d, karelia d n, pandey m k, et al. design, synthesis, and biological evaluation of novel selenium (se-nsaid) molecules as anticancer agents[j]. journal of medicinal chemistry, 2016, 59(5): 1946-1959.
Se-Aspirin Preparation Products And Raw materials
Raw materials
Preparation Products
Se-Aspirin Suppliers
- Tel
- 0371-55900031 18137872243
- Fax
- QQ：2853979815
- 2853979815@qq.com
- Country
- China
- ProdList
- 9988
- Advantage
- 55
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8140
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11974
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 19699
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@apexbt.com
- Country
- United States
- ProdList
- 6251
- Advantage
- 58