5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide

Product Name: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
CAS No.: 676500-67-7
Chemical Name: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Synonyms: Bevenopran;2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]-;CB-5945;ADL-5945;Bevenopran, 10 mM in DMSO;Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945;5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide;5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
CBNumber: CB03161690
Molecular Formula: C20H26N4O4
Formula Weight: 386.44
MOL File: 676500-67-7.mol

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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Property

Melting point:: 133 - 136 °C
Boiling point:: 575.0±50.0 °C(Predicted)
Density: 1.204±0.06 g/cm3(Predicted)
storage temp.: Refrigerator, under inert atmosphere
solubility: Acetonitrile (Slightly), Chloroform (Slightly)
pka: 14.06±0.50(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B335005
Product name: Bevenopran
Packaging: 10mg
Price: $50
Updated: 2021/12/16

Chemenu

Product number: CM254476
Product name: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Purity: 95%+
Packaging: 1g
Price: $234
Updated: 2021/12/16

Crysdot

Product number: CD11074155
Product name: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Purity: 95+%
Packaging: 1g
Price: $248
Updated: 2021/12/16

Alichem

Product number: 676500677
Product name: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Packaging: 1g
Price: $272.5
Updated: 2021/12/16

Chemenu

Product number: CM254476
Product name: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Purity: 95%+
Packaging: 5g
Price: $701
Updated: 2021/12/16

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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Chemical Properties,Usage,Production

Uses

Bevenopran, is a peripheral μ-opioid receptor antagonist.

Definition

ChEBI: Bevenopran is an aromatic ether.

in vivo

Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)^[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively^[1].

IC 50

μ Opioid Receptor/MOR

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Suppliers

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View Lastest Price from 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Bevenopran 676500-67-7
Price: US $65.00-650.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-31

676500-67-7, 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamideRelated Search:

5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide

2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]-

Bevenopran

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide

ADL-5945

CB-5945

Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945

Bevenopran, 10 mM in DMSO

676500-67-7