ChemicalBook > CAS DataBase List > Boc-Aminooxy-PEG2-Azide

Boc-Aminooxy-PEG2-Azide

Product Name
Boc-Aminooxy-PEG2-Azide
CAS No.
252378-68-0
Chemical Name
Boc-Aminooxy-PEG2-Azide
Synonyms
Boc-NH-O-PEG3-N3;Boc-Aminooxy-PEG2-Azide;t-Boc-Aminooxy-PEG2-azide;t-Boc-Aminooxy-PEG2-azide boc
CBNumber
CB03162899
Molecular Formula
C11H22N4O5
Formula Weight
290.31618
MOL File
252378-68-0.mol
More
Less

Boc-Aminooxy-PEG2-Azide Property

storage temp. 
Storage temp. 2-8°C
form 
Viscous Liquid
color 
Colorless to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

BroadPharm
Product number
BP-22994
Product name
t-Boc-Aminooxy-PEG2-azide
Purity
98%
Packaging
250mg
Price
$480
Updated
2021/12/16
BroadPharm
Product number
BP-22994
Product name
t-Boc-Aminooxy-PEG2-azide
Purity
98%
Packaging
1g
Price
$1400
Updated
2021/12/16
More
Less

Boc-Aminooxy-PEG2-Azide Chemical Properties,Usage,Production

Description

t-Boc-Aminooxy-PEG2-azide is a click chemistry crosslinker molecule. The azide group enables PEGylation via Click Chemistry. The protected aminooxy can be deprotected under acidic conditions and then can react with an aldehyde or ketone group to form a stable oxime linkage.

Uses

t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. t-Boc-Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Boc-Aminooxy-PEG2-Azide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Boc-Aminooxy-PEG2-Azide Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
More
Less

View Lastest Price from Boc-Aminooxy-PEG2-Azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
t-Boc-Aminooxy-PEG2-azide 252378-68-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-22

252378-68-0, Boc-Aminooxy-PEG2-AzideRelated Search:


  • Boc-Aminooxy-PEG2-Azide
  • t-Boc-Aminooxy-PEG2-azide
  • t-Boc-Aminooxy-PEG2-azide boc
  • Boc-NH-O-PEG3-N3
  • 252378-68-0