Olcegepant (hydrochloride)

Product Name: Olcegepant (hydrochloride)
CAS No.: 586368-06-1
Chemical Name: Olcegepant (hydrochloride)
Synonyms: BIBN-4096 hydrochloride;BIBN4096BS hydrochloride;BIBN-4096BS hydrochloride;BIBN 4096BS hydrochloride;Olcegepant (hydrochloride);BIBN-4096 HYDROCHLORIDE; BIBN-4096BS HYDROCHLORIDE; BIBN4096BS HYDROCHLORIDE; BIBN 4096BS HYDROCHLORIDE
CBNumber: CB03167627
Molecular Formula: C38H48Br2ClN9O5
Formula Weight: 906.12
MOL File: 586368-06-1.mol

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Olcegepant (hydrochloride) Property

storage temp.: Store at -20°C
form: Solid
color: Light yellow to yellow
Water Solubility: Water: ≥ 66.66 mg/mL (73.57 mM)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6321
Product name: Olcegepant(hydrochloride)
Purity: 99.31%
Packaging: 5mg
Price: $192
Updated: 2021/12/16

ChemScene

Product number: CS-6321
Product name: Olcegepant(hydrochloride)
Purity: 99.31%
Packaging: 10mg
Price: $324
Updated: 2021/12/16

ChemScene

Product number: CS-6321
Product name: Olcegepant(hydrochloride)
Purity: 99.31%
Packaging: 50mg
Price: $1355
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573103
Product name: Olcegepant hydrochloride
Purity: >98%
Packaging: 100mg
Price: $1356.6
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573103
Product name: Olcegepant hydrochloride
Purity: >98%
Packaging: 250mg
Price: $2691.1
Updated: 2021/12/16

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Olcegepant (hydrochloride) Chemical Properties,Usage,Production

Biological Activity

Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective calcitonin gene-related peptide (CGRP) antagonist with a Ki value of 14.4 pM for human CGRP.

in vivo

Olcegepant (BIBN4096BS) in doses between 1 and 30 μg/kg (i.v.) inhibits the effects of CGRP, released by stimulation of the trigeminal ganglion, on facial blood flow in marmoset monkeys. Pre-treatment with Olcegepant (900 μg/kg) inhibits the capsaicin-induced expression of Fos throughout the spinal trigeminal nucleus by 57%.

target

IC50: 0.03 nM (CGRP1)
Ki: 14.4 pM (hCGRP)

Olcegepant (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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Olcegepant (hydrochloride) Suppliers

China 11 United States 3 USA 1 Global 15

ShangHai Angti Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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DC Chemicals

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Beijing Jin Ming Biotechnology Co., Ltd.

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Kaifeng Mingren Pharmaceutical Co.,LTD

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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

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Nanjing Shizhou Biology Technology Co.,Ltd

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586368-06-1, Olcegepant (hydrochloride)Related Search:

Olcegepant (hydrochloride)

BIBN 4096BS hydrochloride

BIBN-4096 hydrochloride

BIBN-4096 HYDROCHLORIDE; BIBN-4096BS HYDROCHLORIDE; BIBN4096BS HYDROCHLORIDE; BIBN 4096BS HYDROCHLORIDE

BIBN4096BS hydrochloride

BIBN-4096BS hydrochloride

586368-06-1