(-)-Sparteine sulfate pentahydrate Property

Melting point:

133-140 °C(lit.)

alpha 

-28 º (589nm, c=2, H2O 25 ºC)

refractive index 

-22 ° (C=5, H2O)

storage temp. 

2-8°C

solubility 

H₂O: 0.1 g/mL, clear, colorless

Merck 

8737

CAS DataBase Reference

6160-12-9

Safety

Hazard Codes 

Xn

Risk Statements 

22-20/21/22

Safety Statements 

36-24/25

WGK Germany 

3

RTECS 

WG6430000

HS Code 

29399900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

(-)-Sparteine sulfate pentahydrate Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powder

Uses

oxytocic

Purification Methods

Recrystallise the sulfate from aqueous EtOH or H2O, although the solubility in the latter is high. The free (-)-base has b 173o/8mm and is steam volatile but resinifies in air. The dipicrate forms yellow needles from EtOH/Me2CO, m 205-206o [Clemo et al. J Chem Soc 429 1931; see also Bolnmann & Schuman The Alkaloids (Ed Manske) Vol 9 175 1967]. The free (±)-base has m 71-72.5o [van Tamelen & Foltz J Am Chem Soc 82 2400 1960]. [Beilstein 23 II 99, 23 III/IV 18.]